Results 11 to 20 of about 122,684 (358)

Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma [PDF]

Iranian Journal of Otorhinolaryngology, 2019
Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor ...
Pawel Burduk, Piotr Sawicki, Lukasz Szylberg, Magdalena Bodnar, Andrzej Marszalek   +4 more
doaj   +1 more source

Determination of the Accuracy of Salivary Biomarkers for Periodontal Diagnosis

Diagnostics, 2022
Background: We aimed to investigate the accuracy of salivary matrix metalloproteinases (MMP)-8 and -9, and tissue inhibitor of metalloproteinase (TIMP)-1 in diagnosing periodontitis and in distinguishing periodontitis stages (S)1 to S3.
Hiba Abdullah Mohammed, Ali Abbas Abdulkareem, Faraedon Mostafa Zardawi, Sarhang Sarwat Gul   +3 more
doaj   +1 more source

Relationships between Circulating Matrix Metalloproteinases, Tissue Inhibitor TIMP-2, and Renal Function in Patients with Myocarditis

Kidney & Blood Pressure Research, 2021
Introduction: Under physiological conditions, the myocardial extracellular matrix (ECM) is maintained by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). However, changes in the balance between MMPs and TIMPs can lead
Małgorzata Kobusiak-Prokopowicz, Konrad Kaaz, Dominik Marciniak, Bożena Karolko, Andrzej Mysiak   +4 more
doaj   +1 more source

Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination. [PDF]

Proc Natl Acad Sci U S A, 2020
Houben E, Janssens K, Hermans D, Vandooren J, Van den Haute C, Schepers M, Vanmierlo T, Lambrichts I, van Horssen J, Baekelandt V, Opdenakker G, Baron W, Broux B, Slaets H, Hellings N.   +14 more
europepmc   +2 more sources

Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]

Arhiv za farmaciju, 2017
Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina, Stefanović Aleksandra, Kotur-Stevuljević Jelena, Jelić-Ivanović Zorana, Spasić Slavica, Videnović-Ivanov Jelica, Mihailović-Vučinić Violeta   +6 more
doaj   +1 more source

Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors [PDF]

Journal of Biological Chemistry, 2007
The sarafotoxins and endothelins are approximately 25-residue peptides that spontaneously fold into a defined tertiary structure with specific pairing of four cysteines into two disulfide bonds. Their structures show an interesting topological similarity to the core of the metalloproteinase interaction sites of the tissue inhibitors of ...
Janelle L, Lauer-Fields, Mare, Cudic, Shuo, Wei, Frank, Mari, Gregg B, Fields, Keith, Brew   +5 more
openaire   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases [PDF]

Circulation Research, 2003
Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration.
Visse, R, Nagase, H
openaire   +2 more sources

Role of tissue inhibitor of metalloproteinases-1 in the development of autoimmune lymphoproliferation

Haematologica, 2010
Background Inherited defects decreasing function of the Fas death receptor cause autoimmune lymphoproliferative syndrome and its variant Dianzani’s autoimmune lymphoproliferative disease.
Elena Boggio, Manuela Indelicato, Elisabetta Orilieri, Riccardo Mesturini, Maria Clorinda Mazzarino, Maria Francesca Campagnoli, Ugo Ramenghi, Umberto Dianzani, Annalisa Chiocchetti   +8 more
doaj   +1 more source

Tissue inhibitors of metalloproteinases [PDF]

Genome Biology, 2011
Orchestration of the growth and remodeling of tissues and responses of cells to their extracellular environment is mediated by metalloproteinases of the Metzincin clan. This group of proteins comprises several families of endopeptidases in which a zinc atom is liganded at the catalytic site to three histidine residues and an invariant methionine ...
openaire   +2 more sources

The level of serum matrix metalloproteinase and its prognostic value in closed injuries of the spleen in the immediate postoperative period

Вестник хирургии имени И.И. Грекова, 2022
The OBJECTIVE was to study the state of serum matrix metalloproteinase and their prognostic value in closed spleen injuries in the immediate postoperative period.METHODS AND MATERIALS.
V. V. Masljakov, V. Je. Fedorov, V. Ju. Barsukov, M. A. Shihmagomedov   +3 more
doaj   +1 more source