Results 71 to 80 of about 105,810 (308)

Evaluation of effects caused by differentially spliced Ets-1 transcripts in fibroblasts [PDF]

, 2011
The transcription factor Ets-1 is known to be involved in a broad variety of cellular functions such as cell proliferation, migration, invasion, apoptosis and angiogenesis.
Edwards, Dyaln R., Florin, Alexandra, Fuchs, Tanja, Hahne, Jens Claus, Pourtier, Albin, Soncin, Fabrice, Wernert, Nicolas   +6 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Parameters of the mmp / timp system in assessing the clinical course of pulmonary tuberculoma

Бюллетень сибирской медицины
Aim. To study the parameters of the matrix metalloproteinase (MMP) / tissue inhibitors of metalloproteinase (TIMP) system in assessing the clinical course of pulmonary tuberculoma.Materials and methods.
D. S. Esmedlyaeva, N. P. Alekseeva, M. Ye. Dyakova, D. V. Karostik, I. V. Grigoriev, E. G. Sokolovich   +5 more
doaj   +1 more source

Changes in the extracellular matrix under the influence of anticoagulant therapy in patients with Q-myocardial infarction after thrombolysis

Zaporožskij Medicinskij Žurnal, 2014
Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
doaj   +1 more source

LTD4 and TGF-β1 induce the expression of metalloproteinase-1 in chronic rhinosinusitis via a cysteinyl leukotriene receptor 1-related mechanism [PDF]

, 2016
A
Bachert, Claus, Claeys, Cindy, Holtappels, Gabriële, Perez Novo, Claudina, Pezato, Rogerio   +4 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The impact of changes in serum levels of metalloproteinase-2 and metalloproteinase-9 on pain perception in patients with disc herniation before and after surgery

Journal of Pain Research, 2019
Piotr Kamieniak,1 Joanna Bielewicz,2 Jacek Kurzepa,3 Beata Daniluk,4 Joanna Kocot,3 Tomasz Trojanowski11Department of Neurosurgery, Medical University of Lublin, Lublin, Poland; 2Department of Neurology, Medical University of Lublin, Lublin, Poland ...
Kamieniak P, Bielewicz J, Kurzepa J, Daniluk B, Kocot J, Trojanowski T   +5 more
doaj  

Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis [PDF]

, 2017
Central nervous system tuberculosis (CNS TB) has a high mortality and morbidity associated with severe inflammation. The blood-brain barrier (BBB) protects the brain from inflammation but the mechanisms causing BBB damage in CNS TB are uncharacterized ...
Brilha, Sara, Couraud, Pierre-Olivier, Friedland, Jon S, Ong, Catherine W M, Romero, Nacho, Weksler, Babette   +5 more
core   +3 more sources

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

The relationship between the first episode of wheezing and matrix metalloproteinases-9 and MMP-2 and tissue inhibitors of MMP-1 levels in preterm infants

Annals of Thoracic Medicine, 2013
Aims: Matrix metalloproteinases (MMP) have been associated with neonatal lung morbidity and MMP dysregulation contributes to the pathology of chronic and acute lung disorders.
Rabia Gonul Sezer, Gokhan Aydemir, Abdulkadir Bozaykut, Serdar Hira, Ilhan Asya Tanju, Ömer Özcan   +5 more
doaj   +1 more source