Results 31 to 40 of about 26,024 (216)

Detection and quantification of the giant protein titin by SDS-agarose gel electrophoresis

open access: yesMethodsX, 2017
Titin, a giant sarcomeric protein, is involved in the generation of passive tension during muscle contraction, assembly and stability of the sarcomere in striated muscles. Titin gene produces numerous titin protein isoforms with different sizes (∼3–4 MDa)
Chaoqun Zhu, Wei Guo
doaj   +1 more source

Pengaruh Prone positioning Terhadap Respiratory Rate dan Saturasi Oksigen Pada Bayi Gawat Napas (Respiratory Distress Syndrome ) di Ruang NICU RSUD Gunung Jati Cirebon

open access: yes, 2021
: THE EFFECT OF PRONE POSITIONING ON RESPIRATORY RATE AND OXYGEN SATURATION IN INFANTS WITH RESPIRATORY DISTRESS SYNDROME IN NEONATUS INTENSIVE CARE UNIT AT GUNUNG JATI HOSPITAL CIREBON.
Supriatin, Titin, Nurhayani, Yani
core   +1 more source

The skeletal muscle circadian clock regulates titin splicing through RBM20

open access: yeseLife, 2022
Circadian rhythms are maintained by a cell-autonomous, transcriptional–translational feedback loop known as the molecular clock. While previous research suggests a role of the molecular clock in regulating skeletal muscle structure and function, no ...
Lance A Riley   +12 more
doaj   +1 more source

Inferring the diameter of a biopolymer from its stretching response [PDF]

open access: yes, 2005
We investigate the stretching response of a thick polymer model by means of extensive stochastic simulations. The computational results are synthesized in an analytic expression that characterizes how the force versus elongation curve depends on the ...
MICHELETTI C   +6 more
core   +1 more source

Of cilia, titin, and neurosteroids [PDF]

open access: yesJournal of General Physiology, 2014
This month’s installment of Generally Physiological discusses a calcium compartment in primary cilia, how changes in titin splicing can lead to skeletal muscle myopathy, and a negative feedback loop whereby a neurosteroid protects against hyperactivation of type-1 cannabinoid (CB1) receptors.
openaire   +2 more sources

Modulation of Titin-Based Stiffness by Disulfide Bonding in the Cardiac Titin N2-B Unique Sequence [PDF]

open access: yes, 2009
The giant protein titin is responsible for the elasticity of nonactivated muscle sarcomeres. Titin-based passive stiffness in myocardium is modulated by titin-isoform switching and protein-kinase (PK)A- or PKG-dependent titin phosphorylation.
Garcia-Manes, Sergi   +6 more
core   +1 more source

Titin (Visco-) Elasticity in Skeletal Muscle Myofibrils [PDF]

open access: yes, 2014
Titin is the third most abundant protein in sarcomeres and fulfills a number of mechanical and signaling functions. Specifically, titin is responsible for most of the passive forces in sarcomeres and the passive visco-elastic behaviour of myofibrils and ...
W. Herzog   +3 more
core   +1 more source

Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations

open access: yes, 2021
Heterozygous truncating variants in TTN (TTNtv), the gene coding for titin, cause dilated cardiomyopathy (DCM), but the underlying pathomechanisms are unclear and disease management remains uncertain. Truncated titin proteins have not yet been considered
Gärtner, A.   +27 more
core   +1 more source

Titin contribution to active muscle [PDF]

open access: yes, 2021
The aim of this dissertation is to compare the traditional ‘muscle as motor’ viewpoint to the alternative viewpoint ‘muscle as composite material’. We make three parts to achieve the aim.
Jeong, Siwoo
core   +1 more source

Optomechanical damping of a microcantilever force sensor in liquid [PDF]

open access: yes, 2010
A new instrument, constant deflection atomic force microscopy (CD-AFM) constructed to perform force spectroscopy measurements without mechanical instabilities associated with the use of soft AFM cantilevers has been developed, tested and calibrated ...
Al Zahrani, Khalid Eidah
core   +3 more sources

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