Results 31 to 40 of about 26,024 (216)
Detection and quantification of the giant protein titin by SDS-agarose gel electrophoresis
Titin, a giant sarcomeric protein, is involved in the generation of passive tension during muscle contraction, assembly and stability of the sarcomere in striated muscles. Titin gene produces numerous titin protein isoforms with different sizes (∼3–4 MDa)
Chaoqun Zhu, Wei Guo
doaj +1 more source
: THE EFFECT OF PRONE POSITIONING ON RESPIRATORY RATE AND OXYGEN SATURATION IN INFANTS WITH RESPIRATORY DISTRESS SYNDROME IN NEONATUS INTENSIVE CARE UNIT AT GUNUNG JATI HOSPITAL CIREBON.
Supriatin, Titin, Nurhayani, Yani
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The skeletal muscle circadian clock regulates titin splicing through RBM20
Circadian rhythms are maintained by a cell-autonomous, transcriptional–translational feedback loop known as the molecular clock. While previous research suggests a role of the molecular clock in regulating skeletal muscle structure and function, no ...
Lance A Riley +12 more
doaj +1 more source
Inferring the diameter of a biopolymer from its stretching response [PDF]
We investigate the stretching response of a thick polymer model by means of extensive stochastic simulations. The computational results are synthesized in an analytic expression that characterizes how the force versus elongation curve depends on the ...
MICHELETTI C +6 more
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Of cilia, titin, and neurosteroids [PDF]
This month’s installment of Generally Physiological discusses a calcium compartment in primary cilia, how changes in titin splicing can lead to skeletal muscle myopathy, and a negative feedback loop whereby a neurosteroid protects against hyperactivation of type-1 cannabinoid (CB1) receptors.
openaire +2 more sources
Modulation of Titin-Based Stiffness by Disulfide Bonding in the Cardiac Titin N2-B Unique Sequence [PDF]
The giant protein titin is responsible for the elasticity of nonactivated muscle sarcomeres. Titin-based passive stiffness in myocardium is modulated by titin-isoform switching and protein-kinase (PK)A- or PKG-dependent titin phosphorylation.
Garcia-Manes, Sergi +6 more
core +1 more source
Titin (Visco-) Elasticity in Skeletal Muscle Myofibrils [PDF]
Titin is the third most abundant protein in sarcomeres and fulfills a number of mechanical and signaling functions. Specifically, titin is responsible for most of the passive forces in sarcomeres and the passive visco-elastic behaviour of myofibrils and ...
W. Herzog +3 more
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Heterozygous truncating variants in TTN (TTNtv), the gene coding for titin, cause dilated cardiomyopathy (DCM), but the underlying pathomechanisms are unclear and disease management remains uncertain. Truncated titin proteins have not yet been considered
Gärtner, A. +27 more
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Titin contribution to active muscle [PDF]
The aim of this dissertation is to compare the traditional ‘muscle as motor’ viewpoint to the alternative viewpoint ‘muscle as composite material’. We make three parts to achieve the aim.
Jeong, Siwoo
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Optomechanical damping of a microcantilever force sensor in liquid [PDF]
A new instrument, constant deflection atomic force microscopy (CD-AFM) constructed to perform force spectroscopy measurements without mechanical instabilities associated with the use of soft AFM cantilevers has been developed, tested and calibrated ...
Al Zahrani, Khalid Eidah
core +3 more sources

