Results 231 to 240 of about 11,832,408 (324)

TLR-4 regulates neutrophil trafficking and tumor progression in HNSCC

Laryngo-Rhino-Otologie, 2019
B Uhl, L Mittmann, J Schaubächer, M Canis, K Lauber, CA Reichel   +5 more
openaire   +1 more source

Toll-like receptor 4 (TLR-4) polymorphisms and asthma risk in rural and urban settings: findings from the UK biobank. [PDF]

Ups J Med Sci
Kisiel MA, Rask-Andersen M, Johansson Å, Ek WE, Rask-Andersen A.   +4 more
europepmc   +1 more source

Palmatine inhibits TRIF-dependent NF-kB pathway against inflammation induced by LPS in goat endometrial epithelial cells [PDF]

, 2017
Cheng, Z R, Dong, S, Na, L, Sang, M, Wang, D, Yan, B, Yan, Z, Yang, H, Yang, Z, Zhang, S   +9 more
core  

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress, TLR-4/NF-κB signaling, and necroptosis. [PDF]

Front Pharmacol
Mahmoud AM, Alnasser SM, Abd El-Ghafar OAM, Alruhaimi RS, Althagafy HS, Atwa AM, Hassanein EHM.   +6 more
europepmc   +1 more source

DC‐SIGN reacts with TLR‐4 and regulates inflammatory cytokine expression via NF‐κB activation in renal tubular epithelial cells during acute renal injury

Clinical and Experimental Immunology, 2018
D. Feng, Y. Wang, Y. Liu, L. Wu, X. Li, Y. Chen, Y. Chen, C. Xu, K. Yang, T. Zhou   +9 more
semanticscholar   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Assessment of dermal sensitization by nickel salts in a novel humanized TLR-4 mouse model. [PDF]

J Immunotoxicol
Roach KA, Anderson SE, Waggy C, Aldinger J, Stefaniak AB, Roberts JR.   +5 more
europepmc   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Levistolide a Attenuates Acute Kidney Injury in Mice by Inhibiting the TLR-4/NF-κB Pathway. [PDF]

Drug Des Devel Ther
Shi J, Li S, Yi L, Gao M, Cai J, Yang C, Ma Y, Mo Y, Wang Q.   +8 more
europepmc   +1 more source