Results 61 to 70 of about 11,832,408 (324)
Frontiers in Cellular and Infection Microbiology, 2015 To survive in macrophages, Coxiella burnetii hijacks the activation pathway of macrophages. Recently, we have demonstrated that C. burnetii, via its lipopolysaccharide (LPS), avoids the activation of p38α-MAPK through an antagonistic engagement of Toll ...
Filippo eConti +7 more
doaj +1 more source
Molecular human reproduction, 2019 Prolactin (PRL) plays an important role in trophoblast growth, placental angiogenesis and immunomodulation within the feto-maternal interface, where different cell types secrete PRL and express its receptor. During pregnancy, inflammatory signalling is a
A. Olmos-Ortíz +11 more
semanticscholar +1 more source
Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis [PDF]
, 2014 Parasitic worms are able to survive in their mammalian host for many years due to their ability to manipulate the immune response by secreting immunomodulatory products. It is increasingly clear that, reflecting the anti-inflammatory actions of such worm-
Al-Riyami, L. +3 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]
, 2017 NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina +8 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Peculiarities of Tlr-2 (Arg753gln) and Tlr-4 (Asp299gly) Polymorphism Prevalence in Patients with Acute Brucelleis and Cardiovascular System Diseases [PDF]
, 2019 Currently, there are single data on the relationship between TLR-2 polymorphisms (Arg753Gln) and TLR-4 (Asp299Gly) polymorphisms and susceptibility to brucellosis.
Huseynov, E. M. (Elchin)
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Effects of Toll-Like Receptors 3 and 4 in the Osteogenesis of Stem Cells
Stem Cells International, 2014 Objective. To investigate the effects of Toll-like receptors in stem cell osteogenesis. Methods. Bone marrow mesenchymal stem cells (BMSCs) were divided into the blank group, the TLR-3 activated group, and the TLR-4 activated group.
Chen Qi, Xu Xiaofeng, Wang Xiaoguang
doaj +1 more source
Toll like receptor 2 and 4 expression in peripheral blood mononuclear cells of multiple sclerosis patients [PDF]
, 2014 Background: Multiple sclerosis (MS) is a T cell mediated autoimmune disease with unknown etiology. Appropriate MS therapeutic strategies need thorough understanding of both disease etiology and pathogenesis mechanisms.
Hasheminia, Seyed Javad. +5 more
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