Results 51 to 60 of about 300,160 (284)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Toll-Like Receptors Expression in Follicular Cells of Patients with Poor Ovarian Response [PDF]
International Journal of Fertility and Sterility, 2014 Background Poor ovarian response (POR) to gonadotropin stimulation has led to a significant decline in success rate of fertility treatment. The immune system may play an important role in pathophysiology of POR by dysfunctions of cytokines and the ...
Seyed Abdolvahab Taghavi +4 more
doaj
Медицинская иммунология, 2019 Antiviral research has focused mainly on viral targets. However, cellular targets involved in the viral life cycle and antiviral response are becoming more attractive for research, providing a variety of opportunities for antiviral therapy.
A. A. Nikonova +2 more
doaj +1 more source
Peculiarities of Tlr-2 (Arg753gln) and Tlr-4 (Asp299gly) Polymorphism Prevalence in Patients with Acute Brucelleis and Cardiovascular System Diseases [PDF]
, 2019 Currently, there are single data on the relationship between TLR-2 polymorphisms (Arg753Gln) and TLR-4 (Asp299Gly) polymorphisms and susceptibility to brucellosis.
Huseynov, E. M. (Elchin)
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Trakya University Journal of Natural Sciences, 2019 Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively ...
İhsan Gursel +4 more
doaj +1 more source
Binary black hole coalescence in the extreme-mass-ratio limit: Testing and improving the effective-one-body multipolar waveform [PDF]
, 2011 We discuss the properties of the effective-one-body (EOB) multipolar gravitational waveform emitted by nonspinning black-hole binaries of masses and M in the extreme-mass-ratio limit µ/M = v « 1. We focus on the transition from quasicircular inspiral to
Bernuzzi, Sebastiano +2 more
core +3 more sources
Journal of Leukocyte Biology, 2019 Abstract Discussion on TLR3 triggering in CD4 T cells induces IFN beta and IL10-producing iTregs that suppress food allergy.
openaire +3 more sources
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source