Results 111 to 120 of about 46,970 (197)
Tatsuya Yoshida,1 Takuya Miura,1 Tomoh Matsumiya,2 Hidemi Yoshida,2 Hajime Morohashi,1 Yoshiyuki Sakamoto,1 Akira Kurose,3 Tadaatsu Imaizumi,2 Kenichi Hakamada1 1Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine ...
Yoshida T +8 more
doaj
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
TLR3 and TLR4 complex components.
For each of the three nonprotein molecules involved in forming TLR3 and TLR4 complexes, its name and identifier in the ChEBI reference database is given.
Peter D’Eustachio (727315) +7 more
core +1 more source
Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min +2 more
wiley +1 more source
TLR3 Sensing of Viral Infection
Viral infection is detected by the innate immune system which mounts a rapid semi-selective defence involving inflammation and production of type 1 interferons.
Noel G McElvaney (7895978) +2 more
core +2 more sources
Abstract figure legend CAF origins and plasticity give rise to distinct phenotypes with immunosuppressive functions in colorectal cancer and multiple myeloma. These distinct CAF phenotypes contribute to immunosuppressive tumour microenvironments through ECM remodelling, cytokine signalling and immune regulation.
Hui Mo +4 more
wiley +1 more source
TLR3 knock-out macrophages. Wild type and TLR3 knock-out macrophages were infected with DV1.
(A) Cell lysates and total RNA were collected for analysis. Immunoblotting (IB) and RT-PCR analysis show that DV1 infection is significantly higher in cell line deficient for TLR3.
Hui Hui Wong (358017) +5 more
core +1 more source
Messenger RNA constructs encoding nontumor antigens are proposed to sensitize cold tumors to checkpoint blockade. Observational survival estimates favor vaccination but are heterogeneous, and bias‐focused analyses find no significant difference once time‐zero is aligned. Epitope spreading remains undemonstrated in humans. This review separates what the
Sarfaraz K. Niazi
wiley +1 more source
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing +6 more
wiley +1 more source
The Role of Astrocytes in the Inflammatory Response in Neurodiseases
Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng +3 more
wiley +1 more source

