Results 101 to 110 of about 170,484 (302)

Impact of Human Toll-Like Receptor 4 Gene Polymorphism on Infection with Trichomonas vaginalis

Medical Journal of Babylon
Background: Trichomonas vaginalis (T. vaginalis) is an anaerobic protozoan characterized by functional diagnostic flagella which are important motility tools.
Zainab Waddah Kermasha, Hayam Khalis Al-Masoudi, Suhaila Fadhil Mohammed   +2 more
doaj   +1 more source

MicroRNA Let-7i Regulates Innate TLR4 Pathways in Peripheral Blood Mononuclear Cells of Patients with Ankylosing Spondylitis

, 2023
Liangjie Lu,1 Haiming Fang,1 Mengchao Gu,1 Huihan Wang,2 Qiuxia Yu,3 Aqiong Chen,3 Kai-feng Gan1 1Department of Orthopaedics, Li Huili Hospital Affiliated to Ningbo University, Ningbo, 315040, People’s Republic of China; 2Department of Orthopaedics ...
Lu L, Fang H, Chen A, Gan KF, Yu Q, Gu M, Wang H   +6 more
core  

A role for uric acid and the nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast [PDF]

, 2013
Women with antiphospholipid syndrome (APS) are at risk of recurrent pregnancy loss and obstetrical disorders, such as preeclampsia and intrauterine growth restriction (IUGR).
Vikki M Abrahams, Kavathas, Paula B., Melissa J Mulla, Crina M Boeras, Mulla, Melissa J., Paula B Kavathas, Jan J Brosens, Brosens, Jan J., Boeras, Crina M., Larry W Chamley, Jane E Salmon, Abrahams, Vikki M., Salmon, Jane E., Chamley, Larry W.   +13 more
core   +2 more sources

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Probiotics Alleviate Chemotherapy-Associated Intestinal Mucosal Injury via the TLR4–NFκB Signaling Pathway

Drug Design, Development and Therapy, 2023
Xiaochong Li,1,* Bowen Hu,1,* Jiachen Zheng,2,3 Zhiyong Pan,1 Yuxiang Cai,4 Mingjuan Zhao,1 Xiaoqing Jin,2 Zhi-Qiang Li1 1Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, People’s Republic of China ...
Li X, Hu B, Zheng J, Pan Z, Cai Y, Zhao M, Jin X, Li ZQ   +7 more
doaj  

TOLL-LIKE RECEPTOR-4 (TLR4) GENE POLYMORPHISM IN HARINGHATA BLACK CHICKEN BREED [PDF]

, 2018
The experiment was conducted on Haringhata Black Chicken breed to investigate the polymorphism of exon-2 of Toll-Like Receptor-4 gene. Genomic DNA extracted from 82 birds was used for Polymerase Chain Reaction (PCR). Amplified polymerase chain reaction
Sahoo A.K., Pan S, Baidya S, Bhattacharya D., Ghosh P. R., Sarkar U., Saikhom R, Taraphder S   +7 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Heat shock protein 90 mediates the protective effects of vericiguat on myocardial ischemia/reperfusion injury by inhibiting toll-like receptor 4 and c-Jun N-terminal kinases [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): This study aimed to investigate whether vericiguat exerts a protective effect against myocardial ischemia-reperfusion injury (MIRI) by inhibiting toll-like receptor 4 (TLR4) and c-Jun N-terminal kinases (JNK) activation and whether heat ...
Sijie Pan, Junyan Chen, Dongxiao Wang, Jianjun Meng, Min Wang, Guoqiang Zhong, Zhi-Yu Zeng, Ronghui Tu   +7 more
doaj   +1 more source

TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCG

, 2003
Los receptores tipo Toll (TLR) median la activación celular por parte de los microbios y los productos microbianos. Para estudiar el papel de los TLR en el desarrollo de las respuestas inmunitarias del huésped contra las micobacterias, se infectaron ...
Liang, Michael D., Thomas, Karen E., Fenton, Matthew J., Marty, Aileen M., Andresen, Tonje K., Heldwein, Kurt A., Cuesta Rubio, Natalia, Vogel, Stefanie N.   +7 more
core   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source