IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program [PDF]
Sean E. Doyle +10 more
openalex +1 more source
Perinatal Gut Dysbiosis Reduces Milk Oligosaccharides via LPS‐Mediated Gut–Mammary Signaling in Mice
Maternal gut dysbiosis elevates Gram‐negative bacterial lipopolysaccharide (LPS), which enters circulation and accumulates in mammary tissue. This compromises the blood–milk barrier and suppresses key enzymatic genes, ultimately reducing milk oligosaccharide synthesis and potentially affecting neonatal gut microbiota through breastfeeding.
Man‐Lin Zhou +9 more
wiley +1 more source
<i>Echinococcus granulosus</i> antigen B acts as an LPS-scavenging lipoprotein <i>in vitro,</i> preventing TLR4-mediated activation of dendritic cells. [PDF]
Lagos Magallanes S +10 more
europepmc +1 more source
Filtered Kombucha Tea Rings the Bell for TLR2, TLR4, MYD88, and Dectin-1 in Mice Model of Colitis
Elaheh Mahmoudi +2 more
openalex +2 more sources
This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han +7 more
wiley +1 more source
Adopting orphan receptors: zebrafish Tlr4 homologs mediate responses to group IX/X transition metals. [PDF]
Fox APD +6 more
europepmc +1 more source
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao +8 more
wiley +1 more source
Targeting the Spinal Cord-Brain Axis: Electroacupuncture Mitigates Remote Frontal Cortex Neuroinflammation via HMGB1/TLR4 to Aid Functional Recovery After Spinal Cord Injury. [PDF]
Ning Y +9 more
europepmc +1 more source
Palmatine inhibits TRIF-dependent NF-kB pathway against inflammation induced by LPS in goat endometrial epithelial cells [PDF]
Cheng, Z R +9 more
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