Results 251 to 260 of about 175,490 (344)

Tumor cell‐derived vaccines: Advances, challenges, and future prospects

Interdisciplinary Medicine, EarlyView.
Classification and Optimization Directions for Tumor Cell‐Derived Vaccines. This diagram systematically illustrates the four major categories of tumor cell‐derived vaccines, along with their core optimization strategies. The upper section presents the four primary vaccine types: autologous/allogeneic whole‐cell vaccines (which preserve the complete ...
Jiaye Lu, Yu Meng, Xinwei Shi, Yingchao Zhao, David M. Irwin, Xinyue Zhang, Yiqiao Zhang, Quangang Zhu, Zongguang Tai, Zhongjian Chen   +9 more
wiley   +1 more source

TLR4 rs2149356 Polymorphism in Periodontitis and End-Stage Renal Disease: An Exploratory Analysis in Egyptian Patients. [PDF]

Cells
Abou-Bakr A, Hassanein FEA, Nagi N, Ibrahim M, Mekhemar M.   +4 more
europepmc   +1 more source

Frontline: Control of Anaplasma phagocytophilum, an obligate intracellular pathogen, in the absence of inducible nitric oxide synthase, phagocyte NADPH oxidase, tumor necrosis factor, Toll‐like receptor (TLR)2 and TLR4, or the TLR adaptor molecule MyD88 [PDF]

, 2004
Friederike D. von Loewenich, Diana G. Scorpio, Udo Reischl, J. Stephen Dumler, Christian Bogdan   +4 more
openalex   +1 more source

GATA1 Transcriptionally Upregulates LMCD1, Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/YAP Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) is associated with morbidity and mortality. Ferroptosis is associated with the pathophysiology of SA‐AKI. Here, we investigated the role of LIM and cysteine‐rich domain 1 (LMCD1) in the regulation of ferroptosis during SA‐AKI progression.
You‐Qi Zhang, Wei‐Xia Peng, You‐Fu Li, Peng Lu, Hui Liu, Wen‐Guang Liu   +5 more
wiley   +1 more source

Gut microbiota dysbiosis promotes coronary heart disease comorbid with depression through lipopolysaccharides and Toll-like receptor 4. [PDF]

BMC Microbiol
Pan Y, Luo Y, Wu G, Lu Y, Yang P, Kong P, Zheng C, Wang C, Yang L, Li X.   +9 more
europepmc   +1 more source

Long Noncoding RNA TOB1‐AS1 Represses Cervical Cancer Cell Proliferation, Invasion, and Migration via the MicroRNA‐27a‐3p/Thioredoxin‐Interacting Protein Molecular Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cervical cancer (CC) remains a major global health concern, particularly due to its aggressive nature and limited treatment options in advanced stages. Long noncoding RNA (lncRNA) TOB1‐AS1 has been proposed as a tumor suppressor, yet its regulatory mechanism in CC remains unclear.
Yang Wang, You‐Xiang Hou, Li Xie, Yi‐La Xia, Yi‐Na Wang   +4 more
wiley   +1 more source

Berberine protects against gefitinib-induced liver injury by inhibiting the HMGB1/TLR4/NF-κB pathway. [PDF]

Front Pharmacol
Zhang Q, Li N, Ma X, Qiu Y, Li C, Chen Y.   +5 more
europepmc   +1 more source

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

MiR-135a-3p inhibits the progression of prostate cancer by targeting TLR4. [PDF]

Cancer Biol Ther
Li L, Zhang X.
europepmc   +1 more source

Postprandial Metabolism, Inflammation, and Plasma Bile Acid Kinetics in a Rat Model: Implications for Translational Research

Molecular Nutrition &Food Research, EarlyView.
Sprague‐Dawley rats were used to investigate postprandial metabolic and inflammatory responses following the consumption of an energy‐dense meal. Time‐resolved plasma and liver analyses revealed fluctuations in bile acid levels, particularly cholic acid, along with changes in metabolic intermediates, oxylipins, and inflammatory markers.
Larissa Rodrigues, Carlos M. Donado‐Pestana, Tushar More, Mar Garcia‐Aloy, Gustavo M. Carneiro de Lima, Lucas X. Martins de Oliveira, Urska Vrhovsek, Karsten Hiller, Jarlei Fiamoncini   +8 more
wiley   +1 more source