This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han +7 more
wiley +1 more source
Retraction: Paper "MiR-590 Inhibits Endothelial Cell Apoptosis by Inactivating the TLR4/NF-κB Pathway in Atherosclerosis" by Lei Yang and Chuanyu Gao [Yonsei Med J 2019;60(3):298-307]. [PDF]
europepmc +1 more source
Bisphenol F-TLR4 interaction: uncovering new mechanisms in unexplained miscarriage. [PDF]
Zhang Y.
europepmc +1 more source
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao +8 more
wiley +1 more source
Albumin does not induce IL-6 release and toll-like receptor activation in vitro: Role of endotoxin contamination and biochemical modifications. [PDF]
Paar M +8 more
europepmc +1 more source
High‐purity myricitrin from Chinese bayberry leaves alleviates colonic inflammation by preserving epithelial barrier integrity and reshaping gut microbiota composition. ABSTRACT Polyphenols have been widely recognized for their ability to modulate the host inflammatory response and orchestrate the intestinal microenvironment.
Ji‐Min Lv +7 more
wiley +1 more source
Thyroid-Stimulating Hormone Regulates the Glucose Metabolism in Hepatocytes via Toll-Like Receptor 4/Tollip Pathway. [PDF]
Bao S, Li F, Duan L, Jiang X.
europepmc +1 more source
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
Nicotine Attenuates Chondrocyte Inflammation via the α7nAChR-Mediated Inhibition of the HMGB1/TLR4/NF-κB Signaling Pathway. [PDF]
Lin S, Liu T, Song G, Pan H.
europepmc +1 more source

