Results 111 to 120 of about 16,414 (200)

SNPs in toll-like receptor (TLR) genes as new genetic alterations associated with congenital toxoplasmosis? [PDF]

, 2012
Nearly 40 % of pregnant women are infected with Toxoplasma gondii. Primary infections in pregnant women result, in approximately 30–50 % of patients, in transmission of T.
D. Nowakowska, J. Wilczyński, W. Wujcicka   +2 more
core   +1 more source

Toll‐Like Receptor Polymorphisms Influence Graft‐Versus‐Host Disease and Infection Risk After Single‐Unit Cord Blood Transplantation for Adults

European Journal of Haematology, Volume 116, Issue 1, Page 37-45, January 2026.
ABSTRACT Background Toll‐like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen‐associated and damage‐associated molecular patterns. Genetic polymorphisms in TLR genes can modulate immune responses and have been implicated in the outcomes of allogeneic hematopoietic cell transplantation (HCT).
Takaaki Konuma, Megumi Hamatani‐Asakura, Seiko Kato, Shohei Andoh, Hirona Ichimura, Junichi Kuroda, Kaori Kondo, Kazuaki Yokoyama, Maki Monna‐Oiwa, Yasuhito Nannya, Satoshi Takahashi   +10 more
wiley   +1 more source

CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation [PDF]

, 2013
Particulate ligands including cholesterol crystals and amyloid fibrils induce NLRP3-dependent production of interleukin-1β (IL-1β) in atherosclerosis, Alzheimer's disease and diabetes.
Becker, Christine E., Carpenter, Susan B., Ediriweera, Hasini N., Fitzgerald, Katherine A., Golenbock, Douglas T., Grebe, Alena, Kalantari, Parisa, Latz, Eicke, Moore, Kathryn J., Mullick, Adam E., Ramkhelawon, Bhama, Rayner, Katey J., Sheedy, Frederick J., Stuart, Lynda M.   +13 more
core   +1 more source

Dendritic Cells in the Gastrointestinal System: Division of Labor, Plasticity, and Niche‐Specific Adaptation

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT The intestinal immune system is constantly challenged to distinguish between innocuous dietary antigens, commensal microbiota and intestinal self‐antigens (self‐Ags) versus harmful pathogens and malignant cells. It resides in the intestinal wall itself, Peyer's patches (PPs) and the draining lymph nodes (LNs).
Yixuan D. Zhou, Macy R. Komnick, Daria Esterházy   +2 more
wiley   +1 more source

Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells [PDF]

, 2015
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.Mechanical ventilation (MV) of patients can cause
Gudjonsson, Thorarinn, Gudmundsson, Gudmundur Hrafn, Karadottir, Harpa, Karason, Sigurbergur, Kulkarni, Nikhil Nitin   +4 more
core   +3 more sources

Progression of Malaria in the Human Body, Its Effects on the Liver and Its Various Aspects

Advanced Gut &Microbiome Research, Volume 2026, Issue 1, 2026.
Malaria, an infectious disease caused by Plasmodium parasites, is a significant global health issue, particularly in tropical and subtropical regions. Understanding the development of malaria in the human body and its effects on vital organs like the liver is crucial for effective control and prevention.
Avishek Mandal, Sanmoy Karmakar, Mithun Bhowmick, Sweet Naskar, Ankita Sadhukhan, Arnab Sarkar, Prativa Bhowmick, Jiong Yu   +7 more
wiley   +1 more source

Association of Toll-like Receptors 1, 2, 4, 6, 8, 9 and 10 Genes Polymorphisms and Susceptibility to Pulmonary Tuberculosis in Sudanese Patients

ImmunoTargets and Therapy, 2023
Najwa A Mhmoud Faculty of Medical Laboratory Sciences, Department of Medical Microbiology and Immunology, University of Khartoum, Khartoum, SudanCorrespondence: Najwa A Mhmoud, Faculty of Medical Laboratory Sciences, Department of Medical Microbiology ...
Mhmoud NA
doaj  

Profile of toll-like receptor mRNA expression in the choroid plexus in adult ewes [PDF]

, 2014
The blood-cerebrospinal fluid barrier (BCSFB) located in the epithelial cells of the choroid plexus (CP) forms the interface between the cerebrospinal fluid (CSF) and pathogen components circulating in the blood.
Herman, Andrzej, Kowalewska, Marta, Lisiewski, Paweł, Skipor, Janina, Szczepkowska, Aleksandra   +4 more
core   +1 more source

Arctigenin Induces an Activation Response in Porcine Alveolar Macrophage Through TLR6-NOX2-MAPKs Signaling Pathway

Frontiers in Pharmacology, 2018
Arctigenin (ARG), one of the most active ingredients abstracted from seeds of Arctium lappa L., has been proved to exert promising biological activities such as immunomodulatory, anti-viral, and anti-cancer etc.
Zheng Lu, Lingling Chang, Qian Du, Yong Huang, Xiujuan Zhang, Xingchen Wu, Jie Zhang, Ruizhen Li, Zelin Zhang, Wenlong Zhang, Xiaomin Zhao, Dewen Tong   +11 more
doaj   +1 more source

THE ROLE OF TOLL-LIKE RECEPTORS POLYMORPHISM IN ATHEROSCLEROSIS COMPLICATIONS DEVELOPMENT

Российский кардиологический журнал, 2015
Aim. To reveal the association of polymorphic types of Toll-like receptor genes with myocardial infarction (MI), stroke in patients with coronary heart disease (CHD).Material and methods. Totally 292 patients studied, with CHD and anamnesis of stroke and/
O. L. Barbarash, A. S. Golovkin, A. V. Ponasenko, A. G. Kutikhin, I. I. Zhidkova, M. V. Khutornaya, R. R. Salakhov, L. S. Barbarash   +7 more
doaj   +1 more source