Results 101 to 110 of about 18,028 (232)
International Journal of Oncology, 2017 Metastatic chondrosarcoma is a bone malignancy not responsive to conventional therapies; new approaches and therapies are urgently needed. We have previously reported that mTORC1 inhibitor, antitumorigenic cytostatic proline rich polypeptide 1 (PRP-1 ...
K. Galoian +12 more
semanticscholar +1 more source
HemaSphere, Volume 10, Issue 4, April 2026.Abstract Myelodysplastic neoplasms (MDSs) are clonal disorders characterized by ineffective hematopoiesis, dysplasia, and a risk of transformation into acute myeloid leukemia. MDS is also associated with a higher incidence of osteoporosis, suggesting a complex interplay between hematopoiesis, the bone marrow (BM) microenvironment, and bone homeostasis.
Manja Wobus +15 more
wiley +1 more source
Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism [PDF]
, 2015 © 2015 Wiley Periodicals, Inc. Acknowledgement Grant sponsor: State of Lower Saxony-Israel Research Cooperation; Grant number: ZN2035; Grant sponsor:German Research Council; Grant number: SFB/TRR43 and FOR1336; Grant sponsor: Parkinson UK; Grant number ...
Akarasereenont +92 more
core +1 more source
Ecology and Evolution, Volume 16, Issue 3, March 2026.We present the first high‐quality annotated genome of Pinna rudis and an updated genome assembly for Pinna nobilis, two Mediterranean fan mussel species differentially affected by mass mortality events. Comparative genomic analyses of gene sets associated with the “defensome” show that these genes are largely functionally conserved between the two ...
Stéphane Coupé +6 more
wiley +1 more source
SNPs in toll-like receptor (TLR) genes as new genetic alterations associated with congenital toxoplasmosis? [PDF]
, 2012 Nearly 40 % of pregnant women are infected with Toxoplasma gondii. Primary infections in pregnant women result, in approximately 30–50 % of patients, in transmission of T.
D. Nowakowska +2 more
core +1 more source
Ureaplasma parvum lipoproteins, including MB antigen, activate NF-κB through TLR1, TLR2 and TLR6 [PDF]
Microbiology, 2008 Ureaplasma species (Ureaplasma parvum and Ureaplasma urealyticum) are commonly isolated pathogens from the female reproductive tract and are associated with perinatal diseases in humans. Inappropriate induction of inflammatory responses may be involved in the occurrence of such diseases; however, pathogenic agents that induce the inflammatory response ...
Takashi, Shimizu +2 more
openaire +2 more sources
PLoS ONE, 2012 Genetic epidemiological studies of complex diseases often rely on data from the International HapMap Consortium for identification of single nucleotide polymorphisms (SNPs), particularly those that tag haplotypes.
Allison R Baker +13 more
doaj +1 more source
TLR-dependent control of Francisella tularensis infection and host inflammatory responses. [PDF]
PLoS ONE, 2009 BACKGROUND:Francisella tularensis is the causative agent of tularemia and is classified as a Category A select agent. Recent studies have implicated TLR2 as a critical element in the host protective response to F.
Allison L Abplanalp +4 more
doaj +1 more source
Lung organoids as a human system for Mycobacteria infection modeling and drug testing
The FEBS Journal, Volume 293, Issue 6, Page 1587-1611, March 2026.Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza +4 more
wiley +1 more source
Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study [PDF]
, 2012 10.1186/1471-2350-13-66BMC Medical Genetics13 ...
Andiappan, Anand Kumar +8 more
core +3 more sources