Results 121 to 130 of about 148,110 (341)
Toll-like receptors and integrins crosstalk
Frontiers in ImmunologyImmune system recognizes invading microbes at both pathogen and antigen levels. Toll-like receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions of TLRs include cytokine and chemokine production.
Fahd Alhamdan +8 more
doaj +1 more source
Role of TLRs and DAMPs in allograft inflammation and transplant outcomes
Nature Reviews Nephrology, 2016 Graft inflammation impairs the induction of solid organ transplant tolerance and enhances acute and chronic rejection. Elucidating the mechanisms by which inflammation is induced after organ transplantation could lead to novel therapeutics to improve ...
F. Braza +3 more
semanticscholar +1 more source
Pressure‐Induced Drift Artifacts in Stretchable Liquid Metal ThinFilm Electrocardiogram Electrodes
Advanced Science, EarlyView.A stretchable LM electrode integrated with a strain sensor enables in situ quantitative investigation of drift artifact and skin deformation. This reveals the significance of pressure‐induced drift artifact and its intimate relationship with the skin potential model.
Ding Li +13 more
wiley +1 more source
Neighbour-joining phylogenetic analysis of TLRs. [PDF]
, 2015 Ten TLR amino acid sequences of the koala compared to TLRs in eight species, including three eutherians (human, cattle and house mouse), two marsupials (Tasmanian devil and gray short-tailed opossum), chicken, Xenopus and zebrafish.
Katherine Belov (14402) +7 more
core +1 more source
Toll-like receptors of deuterostome invertebrates
Frontiers in Immunology, 2012 Defensive systems against pathogens are responsible not only for survival or lifetime of an individual but also for the evolution of a species. Innate immunity is expected to be more important for invertebrates than mammals, given that adaptive immunity ...
Honoo eSatake, Toshio eSekiguchi
doaj +1 more source
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
Advanced Science, EarlyView.PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
Comprehensive survey and genomic characterization of Toll-like receptors (TLRs) in channel catfish, Ictalurus punctatus: identification of novel fish TLRs [PDF]
, 2013 International audienceA comprehensive survey of channel catfish Toll-like receptors (TLRs) was undertaken following a genomic PCR approach based on degenerate primers. Twenty different TLRs were identified in channel catfish.
Quiniou, Sylvie M. A. +2 more
core +1 more source
Prophylactic Use of Chloroquine May Impair Innate Immune System Response against SARS-Cov-2 [PDF]
Pharmaceutical Sciences, 2020 Hamid Soraya
doaj +1 more source
TLRs, future potential therapeutic targets for RA
Autoimmunity Reviews, 2016 Toll like receptor (TLR)s have a central role in regulating innate immunity and in the last decade studies have begun to reveal their significance in potentiating autoimmune diseases such as rheumatoid arthritis (RA).
Hatem A Elshabrawy +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu +6 more
wiley +1 more source