Results 41 to 50 of about 95,151 (305)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Toll-Like Receptor 4 and Inflammatory Micro-Environment of Pancreatic Islets in Type-2 Diabetes Mellitus: A Therapeutic Perspective

Diabetes, Metabolic Syndrome and Obesity, 2020
Zhaoping Wang,1 Xiaolin Ni,1,2 Li Zhang,1 Liang Sun,1 Xiaoquan Zhu,1 Qi Zhou,1 Ze Yang,1 Huiping Yuan1 1The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, People’s Republic of China; 2Graduate School of
Wang Z, Ni X, Zhang L, Sun L, Zhu X, Zhou Q, Yang Z, Yuan H   +7 more
doaj  

TLRs toll for Tregs [PDF]

Journal of Leukocyte Biology, 2019
Abstract Discussion on TLR3 triggering in CD4 T cells induces IFN beta and IL10-producing iTregs that suppress food allergy.
openaire   +3 more sources

Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells-6

, 2011
Copyright information:Taken from "Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells"Molecular Vision 2007;13():1953-1961.Published online 17 Oct 2007PMCID:PMC2185515.
Lili Tu (83770), Xiangtian Zhou (83771), Jia Qu (28271), Xiuming Jin (83768), Yi Lin (49406), Qin Qin (83769)   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Infection of Human Macrophage-Like Cells by African Swine Fever Virus

Frontiers in Bioscience-Landmark
Background: The African swine fever (ASF) virus (ASFV) and ASF-like viral sequences were identified in human samples and sewage as well as in different water environments. Pigs regularly experience infections by the ASFV.
Zaven A. Karalyan, Susanna A. Ghonyan, Davit A. Poghosyan, Lina H. Hakobyan, Hranush R. Avagyan, Aida S. Avetisyan, Liana O. Abroyan, Arpine A. Poghosyan, Sona A. Hakobyan, Gayane P. Manukyan   +9 more
doaj   +1 more source

Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells-0

, 2011
Copyright information:Taken from "Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells"Molecular Vision 2007;13():1953-1961.Published online 17 Oct 2007PMCID:PMC2185515.
Lili Tu (83770), Xiangtian Zhou (83771), Jia Qu (28271), Xiuming Jin (83768), Yi Lin (49406), Qin Qin (83769)   +5 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells-3

, 2011
Copyright information:Taken from "Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells"Molecular Vision 2007;13():1953-1961.Published online 17 Oct 2007PMCID:PMC2185515 ...
Lili Tu (83770), Xiangtian Zhou (83771), Jia Qu (28271), Xiuming Jin (83768), Yi Lin (49406), Qin Qin (83769)   +5 more
core   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source