Results 21 to 30 of about 97,388 (162)

DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression

Viruses, 2020
Duck tembusu virus (DTMUV) is a single-stranded, positive-polarity RNA flavivirus that has caused considerable economic losses in China in recent years.
Hongyan Guo, Anchun Cheng, Xingcui Zhang, YuHong Pan, Mingshu Wang, Juan Huang, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Ying Wu, Qiao Yang, Shaqiu Zhang, Yanling Yu, Leichang Pan, Bin Tian, Mujeeb Ur Rehman, Xiaoyue Chen, Yunya Liu, Ling Zhang, Zhongqiong Yin, Bo Jing, Renyong Jia   +22 more
doaj   +1 more source

Two non-mammalian toll-like receptors (TLR21 and TLR22) from golden pompano (Trachinotus ovatus): Molecular cloning, gene characterization and expression analysis

Aquaculture Reports, 2021
Toll-like receptors (TLRs), important pattern recognition receptors (PRRs), involve in recognizing pathogen-associated molecular patterns (PAMPs) and play crucial roles in the host innate immunity.
Shuangshuang Gao, Teng Xu, Ruifeng Qiao, Jianchao Lu, Yang Xu, Shu Hu, Youchuan Wei, Zhitao Qi   +7 more
doaj   +1 more source

Toll-like receptors as a part of osteoarthritis pathophysiology: anti-inflammatory, analgesic and neuroprotective effects

Неврология, нейропсихиатрия, психосоматика, 2021
Toll-like receptors (TLRs) act as receptors for bacterial lipopolysaccharides (LPS) and participate in innate immunity. Excessive TLRs activity leads to chronic inflammation and the development of several comorbid pathologies, including osteoarthritis ...
I. Yu. Torshin, O. A. Gromova, A. M. Lila, L. I. Alekseeva, E. A. Taskina   +4 more
doaj   +1 more source

Of mice and men: Interaction of Corynebacterium diphtheriae strains with murine and human phagocytes

Virulence, 2019
Seven non-toxigenic C. diphtheriae strains and one toxigenic strain were analyzed with regard to their interaction with murine macrophages (BMM) and human THP-1 macrophage-like cells. Proliferation assays with BMM and THP-1 revealed similar intracellular
Dulanthi Weerasekera, Tamara Fastner, Roland Lang, Andreas Burkovski, Lisa Ott   +4 more
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LIGAND INDUCED CHEMOTAXIS OF MACROPHAGE CELL LINE U937

Медицинская иммунология, 2014
Treatment of malignant tumors is among challenging issues of clinical medicine. Dissemination and matestasis of tumor cells plays a major role in oncology, being immediately dependent on chemotaxis of tumor cells.
A. B. Filina, O. A. Svitich, L. V. Gankovskaya, P. A. Labzhinov, T. M. Parfenova, V. V. Zverev   +5 more
doaj   +1 more source

The Association Between Gut Microbiota, Toll-Like Receptors, and Colorectal Cancer

Clinical Medicine Insights: Oncology, 2022
The large number of microbes found in the gut are involved in various critical biological processes in the human body and have dynamic and complex interactions with the immune system.
Yongkun Fang, Cheng Yan, Qi Zhao, Bin Zhao, Yiqun Liao, Yuji Chen, Daorong Wang, Dong Tang   +7 more
doaj   +1 more source

STUDYING THE ROLE OF GENES POLYMORPHISM OF CYTOKINES AND TOLL-LIKE RECEPTORS IN PYODERMA PATHOGENESIS

Известия высших учебных заведений. Поволжский регион: Медицинские науки, 2020
Background. At present many authors associate pathogenesis with the defect in genes polymorphism of key cytokines and the genes defect of Toll-like receptors (TLRs) of congenital immune system.
N. I. Baranova, N. Yu. Alekseeva, N. I. Mikulyak   +2 more
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The role of epithelial cells in atopy pathogenesis

Бюллетень сибирской медицины, 2019
Aim. The study of the mechanisms of atopic disease formation and a model of immunopathogenesis of the atopic diseases.Methods. Determination of surface lymphocytes receptors in peripheral blood of atopic bronchial asthma and atopic dermatitis patients ...
A. N. Kazimirsky, J. M. Salmasi, G. V. Poryadin, O. A. Svitich, B. G. Bragvadze, A. A. Alekseeva, L. V. Gankovskaya   +6 more
doaj   +1 more source

The Role of Toll Like Receptors in Pregnancy [PDF]

International Journal of Fertility and Sterility, 2013
For many years, the innate immunity was of less interest than the adaptive immunity because it was perceived to have secondary importance in the functionality of the immune system.
Elham Amirchaghmaghi, Seyed Abdolvahab Taghavi, Farnaz Shapouri, Shaghayegh Saeidi, Abbas Rezaei, Reza Aflatoonian   +5 more
doaj  

When the allergy alarm bells toll: The role of Toll-like receptors in allergic diseases and treatment

Frontiers in Molecular Biosciences, 2023
Toll-like receptors of the human immune system are specialized pathogen detectors able to link innate and adaptive immune responses. TLR ligands include among others bacteria-, mycoplasma- or virus-derived compounds such as lipids, lipo- and ...
Mario Wenger, Sophie Grosse-Kathoefer, Amin Kraiem, Erica Pelamatti, Natalia Nunes, Lisa Pointner, Lorenz Aglas   +6 more
doaj   +1 more source