Results 21 to 30 of about 148,110 (341)

The Role of Toll-like Receptors (TLRs) and Their Related Signaling Pathways in Viral Infection and Inflammation

open access: yesInternational Journal of Molecular Sciences, 2023
Toll-like receptors (TLRs) belong to a powerful system for the recognition and elimination of pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and other pathogens [...].
R. Kircheis, O. Planz
semanticscholar   +1 more source

In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs

open access: yesJournal of Medical Virology, 2020
Coronavirus disease‐2019 (COVID‐19) outbreak due to novel coronavirus or severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has come out as a major threat for mankind in recent times.
Abhigyan Choudhury, S. Mukherjee
semanticscholar   +1 more source

Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases

open access: yesBrain, behavior, and immunity, 2020
Central nervous system (CNS) innate immunity plays essential roles in infections, neurodegenerative diseases, and brain or spinal cord injuries. Astrocytes and microglia are the principal cells that mediate innate immunity in the CNS. Pattern recognition
Lun Li   +3 more
semanticscholar   +1 more source

RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13

open access: yesAdvancement of science, 2022
The subcellular localization and intracellular trafficking of Toll‐like receptors (TLRs) critically regulate TLRs‐mediated antimicrobial immunity and autoimmunity. Here, it is demonstrated that the E3 ubiquitin ligase RNF115 inhibits the post‐endoplasmic
Zhi-Dong Zhang   +8 more
semanticscholar   +1 more source

Sox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks

open access: yesVirulence, 2021
Toll-like receptors (TLRs) are essential for the protection of the host from pathogen infections by initiating the integration of contextual cues to regulate inflammation and immunity.
Jian Shang   +10 more
doaj   +1 more source

RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)

open access: yesИнфекция и иммунитет, 2014
. The mechanisms of the immune system responding to an infection depend on a complex interrelation between the elements of innate and adaptive immunity. The current understanding of how signaling from innate immunity receptors shapes the adaptive immune ...
I. S. Freidlin
doaj   +1 more source

The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCs) - Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2 [PDF]

open access: yes, 2001
Toll-like receptors (TLRs) have been found to be key elements in pathogen recognition by the host immune system. Dendritic cells (DCs) are crucial for both innate immune responses and initiation of acquired immunity.
Dimmeler, S   +20 more
core   +1 more source

Evaluation of Toll-like receptors expression in terms of colon cancer

open access: yesИсследования и практика в медицине, 2022
Purpose of the study. To evaluate the number of cells with the CD45+/- phenotype expressing Toll-like receptors (TLRs) in tissues of the tumor, peritumoral area and resection line tissues in colon cancer (CC) with various tumor locations.Materials and ...
E. A. Dzhenkova   +13 more
doaj   +1 more source

TLRs as a Promise Target Along With Immune Checkpoint Against Gastric Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Gastric cancer (GC) is one of the most common cancers in the world, and the incidence of gastric cancer in Asia appears to increase in recent years. Although there is a lot of improvement in treatment approaches, the prognosis of GC is poor.
Lin Cui, Xiuqing Wang, Dekai Zhang
semanticscholar   +1 more source

Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells-7 [PDF]

open access: yes, 2011
Copyright information:Taken from "Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of in immortalized human corneal epithelial cells"Molecular Vision 2007;13():1953-1961.Published online 17 Oct 2007PMCID:PMC2185515.
Lili Tu (83770)   +5 more
core   +1 more source

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