Toll-like receptors and their role in the pathogenesis of myasthenia gravis: a comprehensive review [PDF]
Frontiers in ImmunologyMyasthenia gravis (MG) is a chronic autoimmune neuromuscular disorder marked by autoantibody-mediated dysfunction at the neuromuscular junction, resulting in fluctuating muscle weakness. The pathogenesis of MG involves a complex interplay between genetic
Xiaoxiao Zheng +5 more
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Toll-Like Receptor 4 (TLR4) and AMPK Relevance in Cardiovascular Disease [PDF]
Advanced Pharmaceutical Bulletin, 2023 Toll-like receptors (TLRs) are essential receptors of the innate immune system, playing a significant role in cardiovascular diseases. TLR4, with the highest expression among TLRs in the heart, has been investigated extensively for its critical role in ...
Haleh Vaez +3 more
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Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands [PDF]
BioImpacts, 2022 Immunotherapy is considered a promising approach for cancer treatment. An important strategy for cancer immunotherapy is the use of cancer vaccines, which have been widely used for cancer treatment.
Leila Rostamizadeh +6 more
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Virulence, 2021 Toll-like receptors (TLRs) are essential for the protection of the host from pathogen infections by initiating the integration of contextual cues to regulate inflammation and immunity.
Jian Shang +10 more
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RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
Инфекция и иммунитет, 2014 . The mechanisms of the immune system responding to an infection depend on a complex interrelation between the elements of innate and adaptive immunity. The current understanding of how signaling from innate immunity receptors shapes the adaptive immune ...
I. S. Freidlin
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Evaluation of Toll-like receptors expression in terms of colon cancer
Исследования и практика в медицине, 2022 Purpose of the study. To evaluate the number of cells with the CD45+/- phenotype expressing Toll-like receptors (TLRs) in tissues of the tumor, peritumoral area and resection line tissues in colon cancer (CC) with various tumor locations.Materials and ...
E. A. Dzhenkova +13 more
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The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCs) - Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2 [PDF]
, 2001 Toll-like receptors (TLRs) have been found to be key elements in pathogen recognition by the host immune system. Dendritic cells (DCs) are crucial for both innate immune responses and initiation of acquired immunity.
Dimmeler, S +20 more
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Role of Microglia TLRs in Neurodegeneration [PDF]
, 2018 Toll-like receptors (TLRs) are a group of receptors widely distributed in the organism. In the central nervous system, they are expressed in neurons, astrocytes and microglia.
Carla Ribeiro Alvares Batista +9 more
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Role of Toll-Like Receptors in Neuroimmune Diseases: Therapeutic Targets and Problems
Frontiers in Immunology, 2021 Toll-like receptors (TLRs) are a class of proteins playing a key role in innate and adaptive immune responses. TLRs are involved in the development and progression of neuroimmune diseases via initiating inflammatory responses.
Haixia Li +9 more
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Brazilian Journal of Veterinary Pathology, 2011 Malaria is caused by protozoan parasites of the genus Plasmodium, which is transmitted by Anopheline mosquitoes. Experimental murine models using rodent malaria are useful for studying pathologic aspects of severe malaria.
Ana Patrícia C. Silva +4 more
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