Results 61 to 70 of about 95,151 (305)

Toll-Like Receptors and Diabetic Nephropathy: A Review of Recent Advances

Turkish Journal of Immunology
Diabetic nephropathy (DN) is one of the most common kidney diseases, but its exact pathophysiology remains unknown. Toll-like receptors (TLRs) are innate immune receptors that recognize pathogen- and danger-associated molecular patterns, which can result
Mohammad Sadra Gholami Chahkand, Yasaman Tavakoli, Ava Aghakhani, Monireh Askarzadeh, Hosein Azimi, Nogol Ghalamkarpour, Alaleh Alizadeh, Iman Archin, Sajad Kermani, Akram Ansari, Mohadeseh Poudineh, Zahra Mali, Elaheh Foroughi, Gisou Erabi, Seyed Amirhossein Mazhari, Mohammad Sadegh Fallahi, Niloofar Deravi, Parisa Alsadat Dadkhah   +17 more
doaj   +1 more source

New application of anti-TLR monoclonal antibodies: detection, inhibition and protection

Inflammation and Regeneration, 2018
Monoclonal antibody (mAb) is an essential tool for the analysis in various fields of biology. In the field of innate immunology, mAbs have been established and used for the study of Toll-like receptors (TLRs), a family of pathogen sensors that induces ...
Ryutaro Fukui, Yusuke Murakami, Kensuke Miyake   +2 more
doaj   +1 more source

Immunomodulatory responses of toll like receptors against 2019nCoV

Russian Open Medical Journal, 2021
The present review discusses the immune signals via toll like receptors (TLRs) against 2019nCoV. We researched using different database, up to June 18th, 2020. All the included articles were published in English language. The outcome of this review, that
Amany Sayed Maghraby
doaj   +1 more source

Traffic on the TLR expressway

Journal of Experimental Medicine
Genetic variation in UNC93B1, a key component in TLR trafficking, can lead to autoinflammation caused by increased TLR activity. Analysis of seven patient variants combined with a comprehensive alanine screen revealed that different regions of UNC93B1 selectively regulate different TLRs (Rael et al.
Justin Taft, Dusan Bogunovic
openaire   +2 more sources

Eicosanoids in the Innate Immune Response: TLR and Non-TLR Routes

Mediators of Inflammation, 2010
The variable array of pattern receptor expression in different cells of the innate immune system explains the induction of distinct patterns of arachidonic acid (AA) metabolism. Peptidoglycan and mannan were strong stimuli in neutrophils, whereas the fungal extract zymosan was the most potent stimulus in monocyte-derived dendritic cells since it ...
Yolanda Alvarez, Isela Valera, Cristina Municio, Etzel Hugo, Francisco Padrón, Lydia Blanco, Mario Rodríguez, Nieves Fernández, Mariano Sánchez Crespo   +8 more
openaire   +4 more sources

PCR primers of human TLRs.

, 2012
PCR primers of human TLRs.
Ming Xu (151206), Yonghua Zhou (151227), Bing Cai (151199), Zhiqin Qiu (151213), Xiaofeng Han (151229), Yuzheng Huang (151191), Yonghui Tao (151217), Jie Wang (16762), Qi Gao (133189), Jing Yang (13969), Yongliang Xu (151223), Ying Zhang (40767)   +11 more
core   +1 more source

Binding affinity between Vaccine molecules and TLRs by ClusPro server.

, 2023
Binding affinity between Vaccine molecules and TLRs by ClusPro server.
Md. Abdul Khaleque (9565404), Nurul Amin Rani (16493881), Abu Tayab Moin (12754874), Mohammad Najmul Sakib (16955422), Nafisa Nawal (12459057), Md. Asad Ullah (9282071), Rajesh B. Patil (8990963), Talha Zubair (16955416), Tanjin Barketullah Robin (16493866), Syed Iftakhar Mahamud (16955419), Nafisa Nawal Islam (3863530), Abdullah Mohammad Shohael (11837855), Nurul Absar (685660)   +12 more
core   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Dual Role of Toll-like Receptors in Human and Experimental Asthma Models

Frontiers in Immunology, 2018
Asthma is a chronic airway inflammatory disease that is influenced by the interplay between genetic factors and exposure to environmental allergens, microbes, or microbial products where toll-like receptors (TLRs) play a pivotal role.
Amin Zakeri, Amin Zakeri, Momtchilo Russo   +2 more
doaj   +1 more source

Toll-like receptor (TLR) 2 and TLR13 from the endangered primitive-ray finned fish Dabry’s sturgeon (Acipenser dabryanus) and their expression profiling upon immune stimulation

Aquaculture Reports, 2020
Toll-like receptors (TLRs) are important pattern recognition receptors (PRRs) which can recognize a series of pathogen associated molecular patterns (PAMPs) to initiate the host innate immune responses.
Rong Tang, Sisi Wang, Panpan Han, Qihuan Zhang, Shuhuan Zhang, Xiaoping Xing, Rong Shao, Wei Xu, Qiaoqing Xu, Qiwei Wei, Zhitao Qi   +10 more
doaj   +1 more source