Results 81 to 90 of about 97,388 (162)

EVOLUTION, CLASSIFICATION, AND BIOCHEMICAL FOUNDATIONS OF TOLL-LIKE RECEPTORS (TLRS) AND THEIR ROLE IN CHYTRIDIOMYCOSIS RESISTANCE [PDF]

open access: yes, 2021
Chytridiomycosis, a disease caused by the fungus Batrachochytrium dendrobatidis (Bd), is a major concern for Amphibian populations. Over the past thirty years, global declines related to Bd infection have been observed, particularly in neotropical ...
De Leon, Joseph
core  

Toll-Like Receptors, Their Ligands, and Atherosclerosis

open access: yesThe Scientific World Journal, 2011
Atherosclerosis is a disease characterized by inflammation in the arterial wall. Atherogenesis is dependent on the innate immune response involving activation of Toll-like receptors (TLRs) and the expression of inflammatory proteins.
Conrad P. Hodgkinson, Shu Ye
doaj   +1 more source

Toll-Like Receptors: Role in Dermatological Disease

open access: yesMediators of Inflammation, 2010
Toll-like receptors (TLRs) are a class of conserved receptors that recognize pathogen-associated molecular patterns (PAMPs) present in microbes. In humans, at least ten TLRs have been identified, and their recognition targets range from bacterial ...
Aswin Hari   +3 more
doaj   +1 more source

The MDS analysis of evolutionary relationships among chordata, mollusca and arthropoda TLRs.

open access: yes, 2013
The sequences used for MDS analysis are listed in table S2. Different colors are used to distinguish between phylum species. The distance between any two points on the plot refers to their molecular distance or divergence.
Zhiming Xiang (465463)   +6 more
core   +1 more source

NLRs join TLRs as innate sensors of pathogens.

open access: yes, 2005
Pathogen-recognition receptors (PRRs) are key components of immune systems and are involved in innate effector mechanisms and activation of adaptive immunity.
Martinon, F.   +3 more
core   +1 more source

Toll-like receptors (TLRs) and mannan-binding lectin (MBL): On constant alert in a hostile environment

open access: yes, 2011
In the beginning were neither B cells nor T cells nor antibodies, but innate immune defense alone. The primary functional theme of innate immunity is the distinction between self and non-self, which is maintained by a vast number of cellular and ...
Ingrid-Maria Bergman   +1 more
core   +1 more source

From defense to offense: Modulating toll-like receptors to combat arbovirus infections

open access: yesHuman Vaccines & Immunotherapeutics
Arboviruses are a significant threat to global public health, with outbreaks occurring worldwide. Toll-like receptors (TLRs) play a crucial role in the innate immune response against these viruses by recognizing pathogen-associated molecular patterns and
Rafidah Lani   +4 more
doaj   +1 more source

Systematic review of structural and immunological features of mollusk toll-like receptors in aquaculture context

open access: yesFrontiers in Immunology
IntroductionToll-like receptors (TLRs) are transmembrane proteins essential for innate immunity. While vertebrate TLRs have been well studied, knowledge of their distribution, structure, and function in mollusks remains limited, despite their importance ...
Hongyu Li   +10 more
doaj   +1 more source

Correlation analysis between IL-1R/TLRs pathway and superficial dermatomycosis

open access: yes
Objective This study explored the correlation between interleukin-1 receptor/Toll-like receptor (IL-1R/TLRs)-mediated inflammatory signaling pathways and the severity of superficial dermatomycosis.
DongMei Tang   +5 more
core   +1 more source

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza

open access: yes, 2015
SummaryToll-like receptors (TLRs) activate distinct, yet overlapping sets of signaling molecules, leading to inflammatory responses to pathogens.
Joseph R. Lakowicz   +9 more
core   +1 more source

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