Results 71 to 80 of about 95,151 (305)
Blood, 2010 Killer immunoglobulin-like receptors (KIRs) are well-known for binding human leukocyte antigen (HLA) and allowing natural killer (NK) cells to monitor HLA levels on host cells. Unexpectedly, Sivori and colleagues have found that certain KIRs can also bind microbial nucleic acid and deliver it ...
openaire +3 more sources
Inflammation, 2010 Amyloidosis is the major complication of familial Mediterranean fever (FMF). Toll-like receptors (TLR) are involved in the activation of an innate immune system TLR-2 and TLR-4 recognize lipoteichoic acid and lipopolysaccharides (LPS), respectively.
Soylu, Alper +10 more
openaire +4 more sources
, 1993 This presentation describes the upgrades to the Transportable Laser Ranging Systems serial number three (TLRS-3), and the impact that these upgrades will have on the TLRS-3 performance in the field.
Eichinger, Richard +9 more
core
, 2017 Raw sequence alignments and trees used to perform selection analyses in TLRs (Table 1, Table 2 and Figure ...
Edson Ishengoma (3755254) +1 more
core +1 more source
Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis
Advanced Science, EarlyView.Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu +17 more
wiley +1 more source
A Cell Specific Effect of MBOAT7 MAFLD-risk Variant on Immune Cells
Frontiers in Bioscience-LandmarkBackground: Disease risk variants are likely to affect gene expression in a context- and cell-type specific manner. The membrane bound O-acyltransferase domain containing 7 (MBOAT7) rs8736 metabolic-dysfunction-associated fatty liver disease (MAFLD)-risk
Ziyan Pan +4 more
doaj +1 more source
Blood, 2009 AbstractOne of the most fundamental questions in immunology pertains to the recognition of non-self, which for the most part means microbes. How do we initially realize that we have been inoculated with microbes, and how is the immune response ignited?
openaire +3 more sources
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
The Role of Toll-like Receptors (TLRs) Mediated Inflammation in Pancreatic Cancer Pathophysiology
, 2021 Pancreatic cancer (PC) is one of the most lethal forms of cancer, characterized by its aggressiveness and metastatic potential. Despite significant improvements in PC treatment and management, the complexity of the molecular pathways underlying its ...
Arturo Orlacchio, Pellegrino Mazzone
core +1 more source