Results 151 to 160 of about 16,933 (236)

Adipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing

Trimethylamine N-oxide (TMAO) contributes to cardio-metabolic diseases, with hepatic flavin-containing monooxygenase 3 (FMO3) recognized as its primary source.
Yongxia Niu, Baomin Wang, Kenneth King-yip Cheng, Juntao Yuan, Melody Yuen-man Ho, Qizhou Lian, Xiaomu Li, Thashma Ganapathy, Kekao Long, Md Moinul Hoque, Kelvin Ka-lok Wu, Yuyan Zhu, Kai Wang, Xuejia Feng, Martin Wabitsch, Ho, MYM, Li, Xiaomu, Hoque, MM, Lian, Q, Ho, Melody Yuen-man, Feng, X, Niu, Yongxia, Wang, B, Feng, Xuejia, Hoque, Md Moinul, Wabitsch, Martin, Ganapathy, Thashma, Yuan, Juntao, Ganapathy, T, Wang, K, Wu, KKL, Zhu, Y, Cheng, KKY, Wabitsch, M, Lian, Qizhou, Wu, Kelvin Ka-lok, Long, Kekao, Cheng, Kenneth King-yip, Yuan, J, Li, X, Long, K, Wang, Kai, Niu, Y, Wang, Baomin, Zhu, Yuyan   +44 more
core   +1 more source

TMAO at the Crossroads of the Gut-Brain Axis: Emerging Mechanisms Linking Microbiota-Derived Metabolites to Neuroinflammation and Cognitive Dysfunction. [PDF]

Cells
Altahrawi AY, Sofi F, Kanjwal Z, Shah ZA.   +3 more
europepmc   +1 more source

MD SIMULATIONS OF TMAO INTERACTIONS WITH E.COLI 16S RIBOSOMAL RNA

Trimethylamine N-Oxide (TMAO) is an osmolyte that has been extensively characterized through experiments and computational studies for its role in stabilizing proteins under osmotic stress.
Turk, Mitchell Arthur
core  

[Correlation between trimethylamine-N-oxide and cardiovascular metabolic markers]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Zhang H, Peng H, Guo H, Hou T, Li Y, Zheng Y, Tan Y, Ye X, Zhang H, Yu H, Wang X, Fan M, Wu Y, Qin X, Li J, Chen D, Hu Y, Wu T, Wang M.   +18 more
europepmc   +1 more source

Trimethylamine N-Oxide (TMAO) and Atherosclerosis

This monograph provides a concise overview of the emerging role of trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite, in the pathogenesis of atherosclerosis. It reviews the molecular mechanisms linking TMAO with endothelial dysfunction, vascular inflammation, and atherogenesis, together with current and emerging TMAO-targeted ...
openaire   +2 more sources

The Gut-Heart-Kidney Axis in Heart Failure: Trimethylamine N-Oxide and Beyond-A State-of-the-Art Review. [PDF]

Biomedicines
Yusuf IA, Anighoro S, Sultany A, Nawaz S, Adhikari A, Bajpai S, Ullah A, Sharma A, Grover S, Gopireddy NSR, Gondal A, Bernshteyn M, Ghimire S.   +12 more
europepmc   +1 more source

Membrane Raft Redox Signaling Mediates Trimethylamine N-Oxide-Induced NLRP3 Inflammasome Activation and Endothelial Dysfunction. [PDF]

Antioxidants (Basel)
Haque MA, Rahman MA, Sandeep IS, Pasham S, Datta S, Boini KM, Koka S.   +6 more
europepmc   +1 more source

Trimethylamine N-oxide and major adverse cardiac and cerebrovascular events: results of umbrella review and meta-analysis. [PDF]

Nutr Metab (Lond)
Obeid R, Mohr L, White BA, Heine GH, Emrich I, Geisel J, Carter RC.   +6 more
europepmc   +1 more source

The TMAO Metabolic Axis in Vascular Disease: A Position Paper on Redox Mechanisms and Priorities for Clinical Translation. [PDF]

Antioxidants (Basel)
Miceli F, Caradonna E, Panzano C, Mansour W, Ferrara F, Costantino L, Setacci C, di Marzo L.   +7 more
europepmc   +1 more source

Gut-heart-kidney communication in cardiovascular disease: from a single-metabolite hypothesis to a context-dependent metabolite network. [PDF]

Am J Physiol Heart Circ Physiol
Chong L, Rampersaud H, Rao A, Gujare I, Makhijani A, Kim D, Levy E, Beatty B, Kobayashi S.   +8 more
europepmc   +1 more source