Results 11 to 20 of about 25,778 (287)
Trimethylamine N-oxide (TMAO) in human health
EXCLI journal, 2021 Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and diseases, this topic is very popular and is often taken up by researchers. TMAO is a low molecular weight compound that belongs to the class of amine oxides.
Paulina Gątarek +1 more
semanticscholar +3 more sources
TMAO: How gut microbiota contributes to heart failure. [PDF]
Translational Research, 2020 An increasing amount of evidence reveals that the gut microbiota is involved in the pathogenesis and progression of various cardiovascular diseases. In patients with heart failure (HF), splanchnic hypoperfusion causes ischemia and intestinal edema, allowing bacterial translocation and bacterial metabolites to enter the blood circulation via an impaired
Yixin Zhang +3 more
semanticscholar +3 more sources
Journal of Inflammation Research, 2023 Pengxin Ge,1,* Huijie Duan,2,* Chunrong Tao,3,* Sensen Niu,4 Yiran Hu,5 Rui Duan,6 Aizong Shen,7 Yancai Sun,1 Wen Sun3 1Department of Pharmacy, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences
Ge P +8 more
doaj +2 more sources
Background Diet Influences TMAO Concentrations Associated with Red Meat Intake without Influencing Apparent Hepatic TMAO-Related Activity in a Porcine Model [PDF]
Metabolites, 2020 Red meat has been associated with an increased cardiovascular disease (CVD) risk, possibly through gut microbial-derived trimethylamine-N-oxide (TMAO).
Rebekka Thøgersen +7 more
doaj +5 more sources
TMAO: a potential mediator of clopidogrel resistance [PDF]
Scientific Reports, 2021 Trimethylamine-N-oxide (TMAO) can activate platelets and increase thrombosis risk in clinical and experimental models. Meanwhile, the patients with coronary artery disease have higher serum TMAO level.
Ruisong Ma +5 more
doaj +3 more sources
TMAO as a potential biomarker and therapeutic target for chronic kidney disease: A review
Frontiers in Pharmacology, 2022 The gut microbiota and its metabolites have become a hotspot of recent research. Trimethylamine N-oxide (TMAO) metabolized by the gut microbiota is closely related to many diseases such as cardiovascular disease, chronic kidney disease, type 2 diabetes ...
Ye Zixin +24 more
doaj +2 more sources
Trimethylamine-N-Oxide (TMAO) as a Rising-Star Metabolite: Implications for Human Health [PDF]
MetabolitesThe intestinal microbiota, hosting trillions of microorganisms that inhabit the gastrointestinal tract, functions as a symbiotic organism that plays a crucial role in regulating health by producing biologically active molecules that can enter systemic ...
Eugenio Caradonna +11 more
openalex +2 more sources
Hydrophobic association and solvation of neopentane in urea, TMAO and urea–TMAO solutions [PDF]
Physical Chemistry Chemical Physics, 2021 Hydrophobic associations in pure water, urea solution, TMAO solution and urea-TMAO solution were studied using molecular dynamics simulations.
Timir Hajari +2 more
openaire +2 more sources
Gut microbiota derived trimethylamine N-oxide (TMAO) detection through molecularly imprinted polymer based sensor [PDF]
Scientific Reports, 2021 Trimethylamine N-oxide (TMAO), a microbiota-derived metabolite has been implicated in human health and disease. Its early detection in body fluids has been presumed to be significant in understanding the pathogenesis and treatment of many diseases. Hence,
G.B.V.S. Lakshmi +5 more
openalex +2 more sources
Blood, 2020 In this issue of Blood, Wu and colleagues report that trimethylamine N-oxide (TMAO), an intestinal microbiome-dependent metabolite, worsens graft-versus-host disease (GVHD). They further found that TMAO induces M1 polarization of bone marrow–derived macrophages via the nucleotide-binding oligomerization domain–like receptor protein 3 (NLRP3). TMAO is
Eiko, Hayase, Robert R, Jenq
openaire +2 more sources