Results 41 to 50 of about 14,722 (226)

Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice [PDF]

open access: yes, 2021
Patients with chronic kidney disease (CKD) have elevated circulating levels of trimethylamine N-oxide (TMAO), a metabolite derived from gut microbes and associated with cardiovascular diseases.
Karolina Elżbieta Kaczor-Urbanowicz   +29 more
core   +1 more source

Paradox of trimethylamine-N-oxide, the impact of malnutrition on microbiota-derived metabolites and septic patients

open access: yesJournal of Intensive Care, 2021
Background Trimethylamine N-oxide (TMAO) is a microbiota-derived metabolite, which is linked to vascular inflammation and atherosclerosis in cardiovascular (CV) diseases. But its effect in infectious diseases remains unclear. We conducted a single-center
Ruey-Hsing Chou   +12 more
doaj   +1 more source

Atherosclerosis and trimethylamine-N-oxide — the gut microbiota potential

open access: yesРоссийский кардиологический журнал, 2022
Gut dysbiosis contribute to the development of atherosclerosis. Firmicutes contain a trimethylamine-producing gene cluster. The aim was to analyze potential role of trimethylamine-N-oxide (TMAO), gut microbiota metabolite, in the pathogenesis of ...
I. N. Grigorieva
doaj   +1 more source

Trimethylamine N-oxide in atrial fibrillation progression

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2020
The human gut microbiome and its metabolite Trimethylamine N-oxide (TMAO) are sensitive to the human diet and are involved in the complex pathomechanisms that underpin diabetes, obesity, and cardiovascular diseases.
Petra Büttner   +7 more
doaj   +1 more source

Fecal Microbiome Composition Does Not Predict Diet‐Induced TMAO Production in Healthy Adults [PDF]

open access: yes, 2021
Background Trimethylamine-N-oxide (TMAO) is a small molecule derived from the metabolism of dietary nutrients by gut microbes and contributes to cardiovascular disease. Plasma TMAO increases following consumption of red meat.
Wang, Zeneng   +11 more
core   +1 more source

Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C

open access: yesEuropean Journal of Case Reports in Internal Medicine
Trimethylaminuria (TMAU), also known as fish odor syndrome, is a rare metabolic disorder resulting from a deficiency in the enzyme flavin-containing monooxygenase 3, which is responsible for the detoxification of trimethylamine produced during the ...
Martina Knapp
doaj   +1 more source

Double Resolution Model for Studying TMAO/Water Effective Interactions

open access: yes, 2016
The structural properties of water molecules surrounding TMAO molecules are studied using a newly developed atomistic force field for TMAO, combined with a multiscale coarse-graining (MS-CG) force field derived from the atomistic simulations.
Joan-Emma Shea (1235013)   +1 more
core   +2 more sources

Trimethylamine N-Oxide, a Gut Microbiota-Dependent Metabolite, is Associated with Frailty in Older Adults with Cardiovascular Disease [Corrigendum]

open access: yesClinical Interventions in Aging, 2021
He W, Luo Y, Liu JP, et al. Clin Interv Aging. 2020;15:1809– 1820. The authors have advised affiliation 2 on page 1809 is incorrect, the text “Peking Union Medical College” should read “Graduate School of Peking Union ...
He W   +9 more
doaj  

Entropic Stabilization of Proteins by TMAO

open access: yes, 2016
The osmolyte trimethylamine N-oxide (TMAO) accumulates in the cell in response to osmotic stress and increases the thermodynamic stability of folded proteins.
D. Thirumalai (1277850)   +3 more
core   +1 more source

The association between TMAO, CMPF and clinical outcomes in advanced CKD; results from the EQUAL study [PDF]

open access: yes, 2022
Background Trimethylamine N-oxide (TMAO), a metabolite from red meat and fish consumption, plays a role in promoting cardiovascular events. However, data regarding TMAO and its impact on clinical outcomes are inconclusive, possibly due to its ...
Tora Almquist   +275 more
core   +1 more source

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