Results 51 to 60 of about 16,933 (236)
Trimethylamine N-oxide (TMAO) in human health
EXCLI journal, 2021 Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and diseases, this topic is very popular and is often taken up by researchers. TMAO is a low molecular weight compound that belongs to the class of amine oxides. It is formed by the process of oxidation of trimethylamine (TMA) by the hepatic flavin monooxygenases (FMO1 ...
Gatarek, Paulina +1 more
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TMAO, a carnitine-derived metabolite, prolongs the hypertensive effect of Ang II in rats [PDF]
, 2014 Background Recent evidence suggests that an elevated plasma trimethylamine N-oxide (TMAO) level is associated with an increased risk of adverse cardiovascular events in humans; however, the mechanism is not clear.
Sikora, Mariusz +5 more
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Double Resolution Model for Studying TMAO/Water Effective Interactions
, 2016 The structural properties of water molecules surrounding TMAO molecules are studied using a newly developed atomistic force field for TMAO, combined with a multiscale coarse-graining (MS-CG) force field derived from the atomistic simulations.
Joan-Emma Shea (1235013) +1 more
core +2 more sources
Serum Intestinal Metabolites are Raised in Patients with Psoriasis and Metabolic Syndrome
Clinical, Cosmetic and Investigational Dermatology, 2022 Liyun Sun,1,* Xinwei Guo,2,* Yeping Qin,3 Ping Li,4 Chunxia Yu,2 Xuesong Gao,2 Xinran Xie,4 Xuying Xu5 1Dermatology Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of ...
Sun L +7 more
doaj
TMAO Is Both a Biomarker and a Renal Toxin [PDF]
Circulation Research, 2015 In 2011, Hazen and colleagues1 made the seminal discovery that 3 metabolites of dietary phosphatidylcholine (choline, trimethylamine N-oxide [TMAO] and betaine) predicted risk for cardiovascular disease in an independent large clinical cohort. They also demonstrated that supplementing the diet with choline or TMAO promoted atherosclerosis in a mouse ...
openaire +2 more sources
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk [PDF]
, 2016 Normal platelet function is critical to blood hemostasis and maintenance of a closed circulatory system. Heightened platelet reactivity, however, is associated with cardiometabolic diseases and enhanced potential for thrombotic events.
Gupta, Nilaksh +17 more
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Trimethylaminuria in a 58-year-old male with liver cirrhosis and hepatitis C
European Journal of Case Reports in Internal MedicineTrimethylaminuria (TMAU), also known as fish odor syndrome, is a rare metabolic disorder resulting from a deficiency in the enzyme flavin-containing monooxygenase 3, which is responsible for the detoxification of trimethylamine produced during the ...
Martina Knapp
doaj +1 more source
Trimethylamine N-oxide in atrial fibrillation progression
International Journal of Cardiology: Heart & Vasculature, 2020 The human gut microbiome and its metabolite Trimethylamine N-oxide (TMAO) are sensitive to the human diet and are involved in the complex pathomechanisms that underpin diabetes, obesity, and cardiovascular diseases.
Petra Büttner +7 more
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Journal of Inflammation Research, 2023 Pengxin Ge,1,* Huijie Duan,2,* Chunrong Tao,3,* Sensen Niu,4 Yiran Hu,5 Rui Duan,6 Aizong Shen,7 Yancai Sun,1 Wen Sun3 1Department of Pharmacy, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences
Ge P +8 more
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Atherosclerosis and trimethylamine-N-oxide — the gut microbiota potential
Российский кардиологический журнал, 2022 Gut dysbiosis contribute to the development of atherosclerosis. Firmicutes contain a trimethylamine-producing gene cluster. The aim was to analyze potential role of trimethylamine-N-oxide (TMAO), gut microbiota metabolite, in the pathogenesis of ...
I. N. Grigorieva
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