Results 71 to 80 of about 16,933 (236)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

FMO3 allelic variants vs plasma TMAO concentration.

open access: yes, 2016
FMO3 allelic variants vs plasma TMAO concentration.
Allan E. Rettie (219933)   +6 more
core   +1 more source

Association of TMAO levels with indicators of ulcerative colitis activity [PDF]

open access: yesCaspian Journal of Internal Medicine
Background: The diagnosis of ulcerative colitis (UC) today is limited to a small number of biomarkers. Trimethylamine-N-oxide (TMAO) is the product of reactions resulting from the degradation of dietary-free choline, phosphatidylcholine, and carnitine ...
Yelena Laryushina   +4 more
doaj  

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Trimethylamine N-Oxide Generated by the Gut Microbiota Is Associated with Vascular Inflammation: New Insights into Atherosclerosis

open access: yesMediators of Inflammation, 2020
Trimethylamine N-oxide (TMAO) is a biologically active molecule generated by the gut microbiota. Accumulating evidences have indicated a close association between high plasma TMAO levels and the risk of developing atherosclerosis (AS). AS is considered a
Yarong Liu, Min Dai
doaj   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

open access: yesFood Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima   +4 more
wiley   +1 more source

Effects of acute administration of trimethylamine N-oxide on endothelial function: a translational study

open access: yesScientific Reports, 2022
Elevated circulating levels of nutrient-derived trimethylamine N-oxide (TMAO) have been associated with the onset and progression of cardiovascular disease by promoting athero-thrombosis.
Anne Jomard   +11 more
doaj   +1 more source

Potential of Seaweed to Improve the Quality and Shelf Life of Fish and Fishery Products

open access: yesFood Safety and Health, EarlyView.
Growing global demand for safe fish preservation has increased interest in natural alternatives. Seaweed‐derived bioactive compounds possess antioxidant and antimicrobial properties that enhance fish quality, safety, and shelf life. These sustainable preservatives may reduce spoilage and synthetic preservative use, though further research ...
Ashika Banu Rodela   +5 more
wiley   +1 more source

Complex Formation in Aqueous Trimethylamine-N-oxide (TMAO) Solutions

open access: yes, 2012
We study aqueous solutions of the amphiphilic osmolyte trimethylamine-N-oxide (TMAO) using broadband dielectric spectroscopy and femtosecond mid-infrared spectroscopy.
Tielrooij, K.-J.   +6 more
core   +1 more source

Participant characteristics overall and by TMAO Tertiles: (ORIGINS) 2011–2015.

open access: yes, 2020
Participant characteristics overall and by TMAO Tertiles: (ORIGINS) 2011–2015.
Sumith Roy (8308509)   +4 more
core   +1 more source

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