Results 81 to 90 of about 12,371 (198)

Four Haylages, One Metabonome: Defining Diet Driven Metabolic Shifts in Ponies

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Haylage is widely fed to all categories of stabled horses across Europe and New Zealand. Haylage can vary from high energy nutrient dense forage to low energy highly fibrous fodder, yet little is known about the impact different haylages have on metabolism in horses.
Meriel Moore‐Colyer, Pat Harris, Simon Daniels   +2 more
wiley   +1 more source

Lifelong TMAO exposure exerts hypotensive effects in aged spontaneously hypertensive rats

Frontiers in Cardiovascular Medicine
Trimethylamine N-oxide (TMAO), a bacterial metabolite associated with cardiovascular risk, has a debated role, with evidence suggesting both harmful and protective effects.
Wojciech Kopacz, Kinga Jaworska, Mateusz Koper, Marcin Ufnal   +3 more
doaj   +1 more source

The Role of torS and torT Transcription in Driving a Bet‐Hedging Strategy for Trimethylamine N‐Oxide Reductase Expression in Escherichia coli

Molecular Microbiology, EarlyView.
Low basal activity of divergent promoters driving transcription of the trimethylamine N‐oxide (TMAO) sensor TorT and kinase TorS is integral to an O2‐regulated bet‐hedging strategy for continued E. coli growth upon the onset of anaerobiosis. This, along with repression by IscR, promotes noise in the TorS to TorT ratio, which is critical for adaptation ...
Erin L. Mettert, Jeffrey N. Carey, Wilma Ross, Mark Goulian, Patricia J. Kiley   +4 more
wiley   +1 more source

Effects of Weight Loss Interventions on Gut Microbiota‐Derived Metabolites Linked to Cardiometabolic Health: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background Gut microbiota‐derived metabolites are emerging as potential mediators between obesity and cardiometabolic conditions. While weight loss interventions modify microbiota composition, their effects on systemic microbial metabolites remain unclear.
Fernando Q. Iorra, Leonardo André Swarowsky Loebens, Andrea Auler, Eduarda Caroline Tasso Nascimento, Beatriz D. Schaan, Patrícia Martins Bock   +5 more
wiley   +1 more source

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

Experimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner, Olli Kärkkäinen, Sabrina Mörkl, Wolfram Müller, Alfred Fürhapter‐Rieger, Kati Hanhineva, Sandra Johanna Holasek   +6 more
wiley   +1 more source

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu, Boya Ouyang, Yi Yuan, Jesus Simal‐Gandara, Hui Cao   +4 more
wiley   +1 more source

Mechanism of TMAO-mediated NLRP3 inflammasome in the pathogenesis of large artery atherosclerosis in the head and neck

徐州医科大学学报
Objective To screen for specific metabolites in patients with large artery atherosclerosis (LAA) in the head and neck and to verify whether these metabolic markers can upregulate the NLR family pyrin domain containing protein 3 (NLRP3) inflammasome to ...
CHEN Zhiren, HUANG Zehua, YANG Meifang, ZHOU Zixuan, CHEN Weiwei, WANG Peian   +5 more
doaj   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, Volume 101, Issue 8, Page 1980-1996, August 2026.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

Gut Microbiota and Ischemic Stroke: From Pre‐Stroke Dysbiosis and Acute‐Phase Changes to Therapeutic Applications

Brain and Behavior, Volume 16, Issue 8, August 2026.
Abstract Purpose Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota–gut–brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut‐brain communication in stroke, establishing gut dysbiosis as an upstream ...
Ruihui Weng, Gaolei Dong, Jianxin Tang, Yu Zhao   +3 more
wiley   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source