Results 91 to 100 of about 12,371 (198)

Study on the Effect of Trimethylamine Oxide on Recurrent Cerebral Infarction of Minor Ischaemic Stroke Rats

Cerebrovascular Diseases Extra
Introduction: This study investigates the impact of trimethylamine oxide (TMAO) on recurrent cerebral infarction in minor ischaemic stroke (MIS). Methods: A rat model was used, with dietary choline levels adjusted to vary TMAO levels. TMAO was
Chen Chen, Ziwei Hou, Hong Liu, Jintao Wang, Jianyong Guo, Ting Yang, Min Wang, Ling Ding   +7 more
doaj   +1 more source

Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
Cardiovascular disease arises from lifelong accumulation of traditional and emerging risk factors that converge on shared pathophysiological pathways, leading to diverse clinical outcomes, and can be mitigated through integrated screening, prevention, and precision therapies. ABSTRACT Cardiovascular diseases (CVDs) remain the leading cause of morbidity
Mowei Kong, Zaiyong Zheng, Min Huang, Shengyu Huang, Xingwei Zhao, Yang Yu, Chunxiang Zhang   +6 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Network and Experimental Pharmacology on Mechanism of Yixintai Regulates the TMAO/PKC/NF-κB Signaling Pathway in Treating Heart Failure

Drug Design, Development and Therapy
Ziyan Wang,1,2,* Chengxin Liu,1,2,* Jiaming Wei,2,3 Hui Yuan,1,2 Min Shi,2,3 Fei Zhang,2,3 Qinghua Zeng,2,3 Aisi Huang,2,3 Lixin Du,4 Ya Li,4 Zhihua Guo2,3 1First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine ...
Wang Z, Liu C, Wei J, Yuan H, Shi M, Zhang F, Zeng Q, Huang A, Du L, Li Y, Guo Z   +10 more
doaj  

Role of Trimethylamine N-Oxide in Heart Failure

Reviews in Cardiovascular Medicine
Heart failure (HF) is a clinical syndrome characterizing by typical physical signs and symptomatology resulting from reduced cardiac output and/or intracardiac pressure at rest or under stress due to structural and/or functional abnormalities of the ...
Lele Jing, Honghong Zhang, Qiannan Xiang, Huilin Hu, Changlin Zhai, Suining Xu, Hongen Tian   +6 more
doaj   +1 more source

Role of Trimethylamine N‐Oxide in Assessing Plaque Instability of the Culprit Lesion in Chinese Patients With ST‐Elevation Myocardial Infarction: Insights From a 7‐Year Long‐Term Follow‐Up Study

Clinical and Translational Science
This study investigated the relationship between trimethylamine N‐oxide (TMAO) levels and plaque instability in Chinese patients with ST‐elevation myocardial infarction (STEMI) using optical coherence tomography (OCT), with a 7 ‐year follow‐up.
Lili Xiu, Peng Zhao, Xia Gu, Bo Yu
doaj   +1 more source

Trimethylamine N-Oxide, a Gut Microbiota-Dependent Metabolite, is Associated with Frailty in Older Adults with Cardiovascular Disease

Clinical Interventions in Aging, 2020
Wei He,1,2 Yao Luo,1 Jun-Peng Liu,1 Ning Sun,1 Di Guo,1 Ling-Ling Cui,1 Pei-Pei Zheng,1 Si-Min Yao,1 Jie-Fu Yang,1,2 Hua Wang1,2 1Department of Cardiology, Beijing Hospital, National Center of Gerontology, Beijing, People’s Republic of China ...
He W, Luo Y, Liu JP, Sun N, Guo D, Cui LL, Zheng PP, Yao SM, Yang JF, Wang H   +9 more
doaj  

Trimethylamine N-oxide, S-equol, and indoxyl sulfate inflammatory microbiota players in ocular Behçet’s disease

Türk Biyokimya Dergisi
The aims of the study were to assess the levels of serum TMAO, S-equol, and indoxyl sulfate in subjects with ocular active Behçet’s disease (OABD) and ocular inactive Behçet’s disease (OIBD).
Arslan Sermal, Kaya Mehmet Kaan, Aydin Suna, Aydin Suleyman   +3 more
doaj   +1 more source

TMAO and diabetes: from the gut feeling to the heart of the problem

Nutrition & Diabetes
Abstract Elevated plasma levels of trimethylamine N-oxide (TMAO)—a compound derived from diet and the gut microbiome—have been widely studied for their association with diabetes risk and their potential role in disease pathophysiology and complications.
Kinga Jaworska, Monika Kuś, Marcin Ufnal   +2 more
openaire   +3 more sources

Urea and TMAO on Lipid Bilayers [PDF]

Biophysical Journal, 2018
Sergio S. Funari, Bernstorff Sigrid, Joana Valerio   +2 more
openaire   +1 more source