Results 51 to 60 of about 25,778 (287)
Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]
, 2019 Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L. +3 more
core +1 more source
Identification and characterization of trimethylamine N-oxide (TMAO) demethylase and TMAO permease in Methylocella silvestris BL2. [PDF]
Environmental microbiology, 2014 Methylocella silvestris, an alphaproteobacterium isolated from a forest soil, can grow on trimethylamine N-oxide (TMAO) as a sole nitrogen source; however, the molecular and biochemical mechanisms underpinning its growth remain unknown. Marker-exchange mutagenesis enabled the identification of several genes involved in TMAO metabolism, including ...
Zhu, Yijun +7 more
openaire +2 more sources
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota
Microbiome, 2018 Background The dietary methylamines choline, carnitine, and phosphatidylcholine are used by the gut microbiota to produce a range of metabolites, including trimethylamine (TMA).
Lesley Hoyles +12 more
doaj +1 more source
Atherosclerosis and trimethylamine-N-oxide — the gut microbiota potential
Российский кардиологический журнал, 2022 Gut dysbiosis contribute to the development of atherosclerosis. Firmicutes contain a trimethylamine-producing gene cluster. The aim was to analyze potential role of trimethylamine-N-oxide (TMAO), gut microbiota metabolite, in the pathogenesis of ...
I. N. Grigorieva
doaj +1 more source
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
, 2020 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
Reduction of trimethylamine N-oxide to trimethylamine by the human gut microbiota: supporting evidence for ‘metabolic retroversion’ [PDF]
, 2015 Dietary sources of methylamines such as choline, trimethylamine (TMA), trimethylamine N-oxide (TMAO), phosphatidylcholine (PC) and carnitine are present in a number of foodstuffs, including meat, fish, nuts and eggs.
Chilloux, J +4 more
core +3 more sources
Copper‐Catalyzed Three‐Component Selective 1,4‐Amino Oxygenation of 1,3‐Dienes
Angewandte Chemie, EarlyView.Enclosed is a copper‐catalyzed selective 1,4‐amino oxgenation of 1,3‐dienes with the presence of a strong Brønsted acid. This three‐component transformation offers a novel and powerful approach to construct (E)‐1,4‐allylic amino oxygenated motifs by the simultaneous installation of structurally diverse alkylamines and alcohols directly onto 1,3‐dienes.
Guangshou Feng +2 more
wiley +2 more sources
Journal of Intensive Care, 2021 Background Trimethylamine N-oxide (TMAO) is a microbiota-derived metabolite, which is linked to vascular inflammation and atherosclerosis in cardiovascular (CV) diseases. But its effect in infectious diseases remains unclear. We conducted a single-center
Ruey-Hsing Chou +12 more
doaj +1 more source
Toxins, 2019 Gut microbiota-dependent Trimethylamine-N-oxide (TMAO) has been reported to be strongly linked to renal function and to increased cardiovascular events in the general population and in Chronic Kidney Disease (CKD) patients.
Caroline C. Pelletier +9 more
doaj +1 more source
Frontiers in Immunology, 2022 Liver fibrosis is one main histological characteristic of nonalcoholic steatohepatitis (NASH), a disease paralleling a worldwide surge in metabolic syndromes with no approved therapies.
Dengcheng Zhou +4 more
semanticscholar +1 more source