Results 71 to 80 of about 25,778 (287)

Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF) [PDF]

, 2018
Aims: Association of elevated circulating levels of trimethylamine N-oxide (TMAO) with adverse outcomes in patients with heart failure (HF) has been described.
Anker, Stefan D., Chan, Daniel C. S., Cleland, John G. F., Dickstein, Kenneth, Filippatos, Gerasimos S., Hillege, Hans L., Jones, Donald J. l., Lang, Chim C., Metra, Marco, Ng, Leong Loke, Ponikowski, Peter, Samani, Nilesh J., Suzuki, Toru, van Veldhuisen, Dirk Jan, Voors, Adriaan A., Yazaki, Yoshiyuki, Zannad, Faiez, Zwinderman, Aeilko H.   +17 more
core   +4 more sources

TMAO enhances TNF-α mediated fibrosis and release of inflammatory mediators from renal fibroblasts

Scientific Reports
Trimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite and TNF-α is proinflammatory cytokine, both known to be associated with renal inflammation, fibrosis and chronic kidney disease.
Kapetanaki Stefania, Kumawat Kumar Ashok, Paramel Varghese Geena, Persson Katarina, Demirel Isak   +4 more
semanticscholar   +1 more source

Gut Microbiota and Ischemic Stroke: The Role of Trimethylamine N-Oxide [PDF]

Journal of Stroke, 2019
Trimethylamine N-oxide (TMAO) is produced when trimethylamine, a waste product of gut microbes, is converted via hepatic flavin monooxygenases. As TMAO is a potential causative factor in various cardiovascular diseases (CVDs) considerable research ...
Hyo Suk Nam
doaj   +1 more source

A New Light on Vitamin D in Obesity: A Novel Association with Trimethylamine-N-Oxide (TMAO) [PDF]

, 2019
: Vitamin D deficiency and obesity are two public health problems extensively exacerbated over the last years. Among the several mechanisms proposed to account for the complex interplay between vitamin D and obesity, one that has gained particular ...
Annunziata, G., Barrea, L., Colao, A., de Alteriis, G., Laudisio, D., Muscogiuri, G., Savastano, S., Tenore, G. C.   +7 more
core   +1 more source

PRMT5 critically mediates TMAO-induced inflammatory response in vascular smooth muscle cells

Cell Death and Disease, 2022
A high plasma level of the choline-derived metabolite trimethylamine N-oxide (TMAO) is closely related to the development of cardiovascular disease. However, the underlying mechanism remains unclear.
He Liu, K. Jia, Zhengnan Ren, Jia Sun, Li-Long Pan   +4 more
semanticscholar   +1 more source

TMAO is Associated with Mortality: Impact of Modestly Impaired Renal Function [PDF]

Scientific Reports, 2017
AbstractTrimethylamine-N-Oxide (TMAO) is a microbiome-related metabolite that is cleared by the kidney and linked to renal function. We explored the relationship between TMAO and all-cause mortality, and determined whether this association was modified by renal function.
Eke G. Gruppen, Erwin Garcia, Margery A. Connelly, Elias J. Jeyarajah, James D. Otvos, Stephan J. L. Bakker, Robin P. F. Dullaart   +6 more
openaire   +3 more sources

Trimethylamine N-oxide promotes the growth of Chinese mitten crab (Eriocheir sinensis), deposition of amines, and activates the mTOR pathway by affecting metabolism of amino acids

Animal Advances
This study was conducted to evaluate the changes in amino acid metabolism and amine deposition in Chinese mitten crab (E. sinensis) fed with a diet containing Trimethylamine N-oxide (TMAO) to promote its growth and flavor. Three diets containing 0% TMAO,
Haokun Hua, Huixing Guo, Wenbin Liu, Zishang Liu, Chaofan He, Yangyang Huang, Xiufei Cao, Wei Xiong, Xi Wang, Yubo Wen, Saiwei Yin, Pengbo Wang, Aimin Wang, Guangzhen Jiang   +13 more
doaj   +1 more source

Integrated Analysis Reveals the Gut Microbial Metabolite TMAO Promotes Inflammatory Hepatocellular Carcinoma by Upregulating POSTN

Frontiers in Cell and Developmental Biology, 2022
Liver cancer has a high mortality rate. Chronic inflammation is one of the leading causes of hepatocellular carcinoma. Recent studies suggested high levels of trimethylamine N-oxide (TMAO) may correlate with increased risk of inflammatory-induced liver ...
Yonglin Wu, Xing-yu Rong, Miaomiao Pan, Tongyao Wang, Han Yang, Xie Chen, Z. Xiao, Chao Zhao   +7 more
semanticscholar   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Relation between TMAOase activity and content of formaldehyde in fillet minces and bellyflap minces from gadoid fishes [PDF]

, 1997
Minced fish is a significant component of a number of frozen fishery products like fish fingers, cakes and patties. Predominately minced fish is produced from gadoid species (Alaska pollack, cod, saithe, hake and others) possessing the enzyme ...
Gonzales-Sotelo, C., Havemeister, W., Jessen, F., Jorgensen, B., Nielsen, M.K., Rehbein, Hartmut, Schubring, Reinhard   +6 more
core