Results 161 to 170 of about 771 (176)

[A dynamic study of influences of TMJOA on TMJ disc].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2003
To learn the changes of TMJ disc positions under the influences of TMJ Osteoarthrosis(TMJOA).The TMJOA experimental animal model was established by 12 goats. The TMJ disc positions were observed and recorded at different intervals, (1 month, 2 months, 3 months, 4 months and 6 months) then the pathological changes of TMJ specimens were also studied ...
G, Chen, B, Hu, D, Wang, X, Tong, T, Li
openaire   +1 more source

Early Intervention of Subchondral Bone Resorption Mitigates Cartilage Degeneration in TMJOA

Journal of Oral Pathology & Medicine
ABSTRACT Background Excessive subchondral bone resorption is a typical manifestation in the early stage of osteoarthritis. This study is to verify whether and when intervening in subchondral bone could alleviate cartilage degeneration of temporomandibular joint osteoarthritis.
Meng‐Nan Cao, Shi‐Yang Feng, Chen‐Chen Gao, Yang Xiao, Yi‐Xin Li, Jie Lei, Kai‐Yuan Fu   +6 more
openaire   +1 more source

Targeting G6PD to mitigate cartilage inflammation in TMJOA: The NOX4-ROS-MAPK axis as a therapeutic avenue

International Immunopharmacology
Chondrocytes, known for their metabolic adaptability in response to varying stimuli, play a significant role in osteoarthritis (OA) progression. Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the pentose phosphate pathway, has recently been found to upregulate in OA chondrocyte.
Hanyu Lin, Kaixun He, Sihui Zhang, Huachen Chen, Chengchaozi Wang, Jie Lu, Yanjing Ou, Wenqian Chen, Yuwei Zhou, Yang Li, Jiang Chen   +10 more
openaire   +2 more sources

BMSC Derived Exosomes Attenuate Apoptosis of Temporomandibular Joint Disc Chondrocytes in TMJOA via PI3K/AKT Pathway

Stem Cell Reviews and Reports
Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) are crucial means of intercellular communication and can regulate a range of biological processes by reducing inflammation, decreasing apoptosis and promoting tissue repair. We treated temporomandibular joint (TMJ) disc chondrocytes with TNF-α and performed local injection of sodium ...
Wenjun, Chen, Futing, Huang, Baoyi, Chen, Huiyi, Lin, Guan, Luo, Weijun, Zhang, Xiaoyu, Zhang, Beining, Zheng, Ziyi, Wang, Shiting, Wei, Jiaxin, He, Chang, Liu   +11 more
openaire   +2 more sources

Combination of hyperlipidemia and 17β‐Estradiol induces TMJOA‐like pathological changes in rats

Oral Diseases, 2023
Yan Zhao, Ye-Hua Gan, Yan Zhao
exaly  

Glycyrrhizin regulates rat TMJOA progression by inhibiting the HMGB1‐RAGE/TLR4‐NF‐κB/AKT pathway

Journal of Cellular and Molecular Medicine, 2022
Wei Fang, Xing Long
exaly  

MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1

Arthritis Research and Therapy, 2020
Huaqiang Zhao
exaly  

Loss of RAP2A Aggravates Cartilage Degradation in TMJOA via YAP Signaling

Journal of Dental Research, 2023
Xi Zheng, Hexu Qi, Yifei Li
exaly  

Inhibiting Hh Signaling in Gli1+ Osteogenic Progenitors Alleviates TMJOA

Journal of Dental Research, 2022
Yang Chai
exaly  

Melatonin Abates TMJOA Chronic Pain by MT2R in Trigeminal Ganglion Neurons

Journal of Dental Research, 2022
exaly