Results 61 to 70 of about 771 (176)

Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review [PDF]

open access: yes, 2022
Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions and due to their involvement in different diseases, including oral inflammatory diseases.
Petrović, Nina, Roganović, Jelena
core   +1 more source

Expression of Notch signaling pathway in temporomandibular osteoarthritis

open access: yes口腔疾病防治, 2017
Objective To investigate the expression of Notch signaling molecules in temporomandibular joint ar⁃ thritis (TMJOA), and to explore the role and mechanism of Notch signaling pathway in the development and progression of TMJOA.
ZHU Song⁃song
doaj   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

open access: yesAdvanced Science, Volume 13, Issue 18, 27 March 2026.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin   +10 more
wiley   +1 more source

Peroxisomal Deficiency Alleviates Temporomandibular Joint Osteoarthritis Cartilage Degradation

open access: yesInternational Dental Journal
Aim or purpose: This study aims to explore the impact of peroxisome on lipid metabolism and its role in the pathological progression of temporomandibular joint osteoarthritis (TMJOA).
Ruiyang Ren   +4 more
doaj   +1 more source

Extracellular Vesicles‐Functionalized Biomaterials for Oral Disease Theragnostics

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Combining EVs with biomaterials enables sustained, targeted delivery and overcomes traditional limitations. EVs show great promise in diagnosing and treating oral diseases, and could transform oral health management strategies. ABSTRACT Oral diseases impair oral function and are closely linked to various systemic conditions.
Zhe Zhao, Yiyu Zeng, Rui Liu, Xuemei Qiu
wiley   +1 more source

Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1

open access: yesFrontiers in Pharmacology, 2022
Temporomandibular joint osteoarthritis (TMJOA) condylar cartilage degeneration and abnormal subchondral bone pathological remodeling induce pain and joint dysfunction, and cartilage degeneration is considered irreversible. Very few therapeutic approaches
Hexu Qi   +9 more
doaj   +1 more source

A web-based system for neural network based classification in temporomandibular joint osteoarthritis [PDF]

open access: yes, 2018
Objective: The purpose of this study is to describe the methodological innovations of a web-based system for storage, integration and computation of biomedical data, using a training imaging dataset to remotely compute a deep neural network classifier of
Budin, F.   +19 more
core   +2 more sources

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Progress of research on the role of primary cilia in cartilage degeneration in temporomandibular joint osteoarthritis [PDF]

open access: yesKouqiang yixue
Temporomandibular joint osteoarthritis (TMJOA) is characterized by progressive cartilage degeneration, subchondral bone remodeling, chronic inflammation in the synovial tissue and osteophyte formation.
LI Gongchen, HU Ziyue, SUN Yao
doaj   +1 more source

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