Results 71 to 80 of about 771 (176)

FSP1/S100A4-Expressing Stem/Progenitor Cells Are Essential for Temporomandibular Joint Growth and Homeostasis [PDF]

The temporomandibular joint (TMJ) is one of the most used joints in the body. Defects and wear in the cartilage of the joint, condyle, and fibrocartilage disc lie at the heart of many common TMJ disorders.
Anthwal, N., Belisova, D, Sumbalova Koledova, Z, Tucker, A. S., Tuwatnawanit, T., Wessman, W   +5 more
core   +2 more sources

Artificial intelligence for detecting temporomandibular joint osteoarthritis using radiographic image data: A systematic review and meta-analysis of diagnostic test accuracy.

PLoS ONE, 2023
In this review, we assessed the diagnostic efficiency of artificial intelligence (AI) models in detecting temporomandibular joint osteoarthritis (TMJOA) using radiographic imaging data.
Liang Xu, Jiang Chen, Kaixi Qiu, Feng Yang, Weiliang Wu   +4 more
doaj   +1 more source

Estrogen signaling impacts temporomandibular joint and periodontal disease pathology [PDF]

, 2020
This work is licensed under a Creative Commons Attribution 4.0 International License.Women experience a higher incidence of oral diseases including periodontal diseases and temporomandibular joint disease (TMD) implicating the role of estrogen signaling ...
Chen, Jing, Johnson, Pamela M., Kister, Karolina, Robinson, Jennifer L., Wadhwa, Sunil, Yin, Michael T.   +5 more
core   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding (Adv. Sci. 29/2025)

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Joint Osteoarthritis Eosinophils are crucial in the progression of temporomandibular joint osteoarthritis (TMJOA). In article number 2416030, Jiang Chen and co‐workers show OVA/IL‐5‐induced eosinophils promote synovial Lumican, which binds chondrocyte Anxa1 to inhibit TGFβ2/Smad2/3 signaling.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Spatial Transcriptomic Atlas Of Temporomandibular Joint Osteoarthritis In Adolescent Mice

International Dental Journal
Aim or purpose: Temporomandibular joint osteoarthritis (TMJOA) in adolescent patients can lead to mandibular developmental disorders and deformities. This study aims to investigate spatial gene expression changes of condylar cartilage under inflammatory ...
Li Qianli
doaj   +1 more source

Research Progress of Osteoarthritis Treatment by Low Intensity Pulsed Ultrasound

Smart Medicine, Volume 4, Issue 2, June 2025.
As a non‐invasive therapeutic modality, LIPUS demonstrates potential in mitigating OA progression. This review synthesizes current evidence of OA pathophysiology, summarizes the mechanism of LIPUS treatment of OA, and proposes synergistic strategies to advanced OA treatment.
Mengtong Guan, Xinyu Zhang, Xinhe Li, Bo Liao, Wang Han, Jindong Tan, Zijie Wang, Lichen Wang, Jieliang Shen, Xiaoyu Han, Dingqun Bai   +10 more
wiley   +1 more source

Artificial Intelligence in Temporomandibular Joint Disorders: An Umbrella Review

Clinical and Experimental Dental Research, Volume 11, Issue 1, February 2025.
ABSTRACT Objectives Given the complexity of temporomandibular joint disorders (TMDs) and their overlapping symptoms with other conditions, an accurate diagnosis necessitates a thorough examination, which can be time‐consuming and resource‐intensive.
Vini Mehta, Snehasish Tripathy, Toufiq Noor, Ankita Mathur   +3 more
wiley   +1 more source

Alpha‐ketoglutarate ameliorates age‐related and surgery induced temporomandibular joint osteoarthritis via regulating IKK/NF‐κB signaling

Aging Cell, Volume 23, Issue 11, November 2024.
This study demonstrates that αKG administration improves condylar cartilage health of middle‐aged/aged mice, and ameliorates pathological changes in a rat model of partial discectomy induced TMJOA. Mechanically, αKG decrease the expressions of p‐IKK and p‐NF‐κB, maintain the homeostasis of cartilage matrix, and exert anti‐aging effects in chondrocyte ...
Xiaoping Ye, Xinping Li, Jin Qiu, Yiwen Kuang, Bingqiang Hua, Xianwen Liu   +5 more
wiley   +1 more source

Trpv4 Activation Aggravates Temporomandibular Joint Osteoarthritis Via P38 Mapk Pathway

International Dental Journal
Aim or purpose: This study aimed to explore the underlying mechanisms after transient receptor potential vanilloid 4 (TRPV4) activation in disc during the progress of temporomandibular joint osteoarthritis (TMJOA).
Xiaotong Yu, Fu-Jia Yang, Yan Gu, Sheng-Jie Cui   +3 more
doaj   +1 more source

Syndecan‐4 inhibition attenuates cartilage degeneration in temporomandibular joint osteoarthritis

Journal of Oral Rehabilitation, Volume 51, Issue 11, Page 2324-2335, November 2024.
SDC4 inhibition significantly ameliorates condylar cartilage degeneration induced by MIA injection in vivo or IL1β stimulation in vitro, which was mediated, at least partly, through P38 and ERK1/2 signaling. Abstract Background Syndecan 4 (SDC4), a type I transmembrane proteoglycan, serves as a critical link between chondrocytes and the extracellular ...
Xiaohua Chen, Feng He, Hongyun Zhang, Yuanjun Ma, Jia Yu, Han Qin, Fan Wu, Zhuo Wang, Ying Zhan, Jing Zhang, Lei Lu, Mian Zhang, Shibin Yu   +12 more
wiley   +1 more source