Results 171 to 180 of about 81,406 (283)

A SUMOylation/immune-related gene signature predicts the prognosis and immunotherapy efficacy of patients with triple-negative breast cancer. [PDF]

PeerJ
Zou P, Xu H, Gao Y, Bai W, Zhao X, Shao S.   +5 more
europepmc   +1 more source

The Clinical Relevance of Lymph Node Ratio for Post‐Mastectomy Radiotherapy in Triple‐Negative Breast Cancer: A Real‐World Analysis With Propensity Score Matching Using SEER Database

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background To define the role of post‐mastectomy radiotherapy (PMRT) in triple‐negative breast cancer (TNBC), employing lymph node ratio (LNR, ratio of positive over excised lymph nodes) to offer personalized treatment strategies for this aggressively behaving cancer type. Methods The study included a total of 6474 women diagnosed with T1‐4 N1‐
Wei‐Hong Zheng, Jia‐Yuan Sun, Jia Kou, Feng‐Yan Li, Guan‐Qiao Li, San‐Gang Wu, Zhen‐Yu He   +6 more
wiley   +1 more source

Contribution of Mesenchymal-like and Epithelial Cellular Subsets to Chemotherapy Resistance in Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Vuong NB, Korolkova OY, Izban MG, Sakwe NI, McIntosh AR, Ball DD, Black PJ, Edwards AD, Ballard BR, Adunyah SE, Sakwe AM.   +10 more
europepmc   +1 more source

Integration Analysis of Bayesian and Machine Learning for Heterogeneity, Biomarkers, and Optimal Combination Regimens of Pucotenlimab in Solid Tumors

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT The efficacy of PD‐1 inhibitor pucotenlimab (HX008) in solid tumors exhibits heterogeneity. This study integrated data from 6 clinical trials (covering gastric/gastroesophageal junction cancer, triple‐negative breast cancer, melanoma, and dMMR/MSI‐H solid tumors) using Bayesian meta‐analysis, machine learning (optimal XGBoost AUC = 0.86), and ...
Yingge He, Changqing Gao, Shiyan Zhang, Yonghui Hao, Shuning He, Ke Peng, Liqi Li   +6 more
wiley   +1 more source

Proteogenomic decoding of chemotherapy resistance in patients with triple-negative breast cancer. [PDF]

Genome Biol
Lee DK, Kim MH, Hwang Y, Kim SG, Ryu WJ, Kim GU, Yun HM, Park S, Lee JD, Han HJ, Kim GM, Kim KH, Park JB, Kim MJ, Koo JS, Kim JY, Park HS, Kim SI, Gee HY, Park S, Sohn J.   +20 more
europepmc   +1 more source

Structural Characterization, β‐Cyclodextrin Polymer Interaction, and Biological Assessment of the N‐Terminal Peptide from the RPD‐1 Big Defensin of Ruditapes p hilippinarum

Chemistry–Methods, Volume 6, Issue 5, May 2026.
Defensins are a large and ancient family of host–defence peptides present across vertebrates, invertebrates, and plants, where they play a crucial role in innate immunity. Among them, big defensins represent a structurally distinctive subfamily characterized by a hydrophobic N‐terminal domain and a cysteine‐rich C‐terminal β‐defensin‐like domain. Here,
Rita Turnaturi, Giuseppa Augello, Giuseppe Nocito, Marcello Tagliavia, Stefania Zimbone, Rosalia Pellitteri, Giuseppina Sabatino, Giuseppe Di Natale, Michele F. M. Sciacca, Milo Malanga, Antonino Mazzaglia, Melchiorre Cervello, Giuseppe Pappalardo   +12 more
wiley   +1 more source

Peripheral Blood IL-6 and STAT3 Gene Expression as Biomarkers Associated with Neoadjuvant Chemotherapy Response in Triple-Negative Breast Cancer: A Prospective Cross-Sectional Study. [PDF]

Breast Cancer (Dove Med Press)
Özdemir K, Muhtaroğlu A, Kamburoğlu MB, Guney Eskiler G, Özman Gökçe Z, Kocer B.   +5 more
europepmc   +1 more source

STK25 inhibits cancer‐associated fibroblast activation to overcome cetuximab resistance in colorectal cancer

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• STK25 deficiency enhanced CAF‐mediated CRC growth via the NF‐κB/AREG/EGFR axis. • STK25 overexpression or AREG antibody overcame CAF‐mediated cetuximab resistance. • CRC patients with high STK25 and low CAFs marker levels might benefit from cetuximab treatment.
Yifan Hou, Jiangbo Chen, Hao Hao, Tongkun Song, Lin Song, Pu Xing, Kai Weng, Yumeng Ran, Xinying Yang, Xiaowen Qiao, Jie Chen, Ruibin Yao, Hong Yang, Lei Chen, Jiabo Di, Kai Xu, Xiangqian Su, Beihai Jiang   +17 more
wiley   +1 more source

A multiparametric magnetic resonance imaging model incorporating the relative apparent diffusion coefficient for preoperative discrimination of triple-negative breast cancer. [PDF]

Am J Transl Res
Fan H, Shao W, Zhou X, Chen Y, Liu Y, Zhou H, Zha J, Wang J, Ma X, Teng Y.   +9 more
europepmc   +1 more source

TNBC invasion: downstream of STAT3

Oncotarget, 2017
Jackson, James G., Lozano, Guillermina
openaire   +1 more source