Results 191 to 200 of about 74,225 (263)

Epigenetic control of cellular plasticity in breast cancer progression

The FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey, Elizabeth Podleszanski, William J. Muller   +2 more
wiley   +1 more source

RAB7A-enriched extracellular vesicles drive early-metastasis and immune evasion in triple-negative breast cancer. [PDF]

Int J Biol Sci
Zhong H, Wang H, Gao W, Zhou Z, Wang S, Huang O, Huang R, Wang Z, Shen K.   +8 more
europepmc   +1 more source

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

NR3C2 suppresses triple-negative breast cancer progression by regulating mitochondrial ROS homeostasis via NDUFB3. [PDF]

Transl Oncol
Shi H, Zeng X, Guo Q, Lin J.
europepmc   +1 more source

UK recommendations for Ki‐67 immunohistochemical staining and interpretation in breast cancer

Histopathology, EarlyView.
Where possible, a validated digital imaging system should be utilized. If this is not available, then intermediate scores (5%–30%) should be thoroughly assessed using the Ki‐67 International Working Group guidance. Difficult cases should be double scored.
Abeer M Shaaban, Andrew Dodson, Emad Rakha, Ian Ellis, Daniel Rea, Cecily Quinn, Elena Provenzano, Sarah Pinder, on behalf of the UK National Coordinating Committee for Breast Pathology (NCCBP), Association of Breast Pathology (ABP) and the UK National External Quality Assessment Scheme for Immunohistochemistry and In Situ Hybridisation (UK NEQAS ICC & ISH)   +9 more
wiley   +1 more source

Transcriptional intermediary factor 1 gamma-based multitarget gene therapeutic strategy for triple-negative breast cancer. [PDF]

Signal Transduct Target Ther
Park H, Kim TY, Yun H, Cha A, Moon D, Yun E, Kim Y, Im SA, Lee DW, Park C, Kim HK, Lee HB, Lee J, Cho NJ, Lee EJ, Kim HS.   +15 more
europepmc   +1 more source

Digital analysis of spatial expression of stromal fibroblast activation protein alpha (FAP) in DCIS

Histopathology, EarlyView.
Digital analysis of FAP expression in DCIS revealed a higher FAP level around DCIS with nearby invasion, comparable to invasive carcinoma. High FAP correlated with nuclear grade, papillary DCIS and HER2 subtype, showing prognostic potential. Introduction The presence of non‐progressing ductal carcinoma in situ (DCIS) cases has raised concerns of ...
Ka Long Leung, Ronald C Chan, Conrad H Lee, Ngou‐Men Wong, Monalyn Marabi, Shirley K Jamidi, Yun‐Bi Ni, Julia Y Tsang, Man‐Chi Eric Fu, Dajiang Guo, Gary M Tse   +10 more
wiley   +1 more source

Siglec-15 promotes a feed-forward loop between TNBC cells and macrophages via the NF-κB/DcR3/CCL18/STAT3 axis. [PDF]

Transl Oncol
Wang S, Wang HQ, Zhao H, Zhao R, Zhao P, Mu Q.   +5 more
europepmc   +1 more source