Cryptocaryone Exhibits ROS/MAPK-Dependent Antiproliferative and Apoptosis-Inducing Effects on Triple-Negative Breast Cancer Cells and Proof-of-Concept Breast Cancer Mouse Model. [PDF]
Chuang YT +6 more
europepmc +1 more source
What's New? Breast cancer incidence in women increases with age, but which subtypes contribute the most at different ages remains unclear. Incidence patterns of breast cancer subtypes are typically under‐reported in population‐based studies due to a high proportion of cases lacking subtype information.
Leo Gkekos +4 more
wiley +1 more source
Amphiphilic Lipid-Single-Stranded DNA Conjugate-Mediated Cell Surface Engineering for Programmable Intercellular Tethering and Immune Synapse Formation. [PDF]
Kim S, Lee CE, Jangid AK, Kim K.
europepmc +1 more source
This consensus, based on the latest evidence‐based medical data, provides guidance on the standardized application and safety management of PARP inhibitors in breast cancer treatment, aiming to serve as a reference for clinical practice. ABSTRACT Breast cancer represents a major threat to women's health in China.
Fei Ma +5 more
wiley +1 more source
Feilike and Its Constituent Licochalcone B Trigger Caspase-3/GSDME-Mediated Pyroptosis in Triple-Negative Breast Cancer via Modulation of the Mutant p53-Calcium/ER Stress-ROS-MAPK Axis. [PDF]
Yang J +8 more
europepmc +1 more source
Real‐World Efficacy of Metronomic Chemotherapy in Advanced Breast Cancer Across Molecular Subtypes
ABSTRACT Objective Metronomic chemotherapy (mCHT) is widely used in the treatment of breast cancer due to its low toxicity and convenience. However, there remain real‐world studies with satisfactory samples focusing on mCHT in advanced breast cancer. Methods Enrolled patients were assigned into capecitabine‐based (X‐based) group and other mCHT group ...
Hanxing Zhou +6 more
wiley +1 more source
Development of predictive models for the prognosis of triple-negative breast cancer using multiple transcriptomic analyses. [PDF]
Hwangbo S, Choi Y, Ryu JY.
europepmc +1 more source
A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis [PDF]
Edwards, John R. +1 more
core +1 more source
MAP kinase activation in TNBC.
We conducted an in vitro screen to identify genes associated with resistance in human TNBC cells to two separate chemotherapeutic agents. MAPK10 and MAPK12 were among the kinases most significantly activated. Other kinases were activated during resistance to chemotherapy, including STK17A.
openaire +1 more source
Neoadjuvant Chemotherapy for Male Breast Cancer: A Retrospective Cohort Study
ABSTRACT The survival benefit of neoadjuvant chemotherapy (Neo‐CT) among male breast carcinoma (MaBC) remains unclear, and the specific population that can benefit from Neo‐CT is also not yet defined. We utilized the data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database and employed Kaplan–Meier analysis;
Zejian Yang +9 more
wiley +1 more source

