Results 201 to 210 of about 51,359 (249)

Breaking Physiological Barriers in Women's Health: Mucoadhesive and Stimuli‐Responsive Nanomaterials

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 5, September/October 2026.
Drug delivery vehicles generated from biomaterials for women's health. In particular, the breast and the reproductive system, including the ovary, uterus, cervix, vagina, and the surrounding tissues, targeted drug delivery. BioRender. ABSTRACT Biomaterials are natural or synthetic molecules that exhibit biocompatibility, biodegradability, or ...
Maddox Parsons, Alivia R. Parker, Luke Schneider, Trisha Sullivan, Brittany E. Givens   +4 more
wiley   +1 more source

Beyond the tumor: the role of the gut microbiome in triple-negative breast cancer. [PDF]

Front Oncol
Saadatkhah A, Nicholson L, Buchholz TA, Hong L.   +3 more
europepmc   +1 more source

Proline‐Derived N‐Heterocyclic Carbene Gold(I) Complexes With Dual DNA Binding and Thioredoxin Reductase Inhibition

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Proline‐derived Au(I)–NHC complexes display potent anticancer activity against lung and triple‐negative breast cancer cells. The cationic complexes promote DNA intercalation, thioredoxin reductase inhibition, ROS overproduction, and mitochondrial membrane depolarization, ultimately triggering apoptotic cell death through a multimodal mechanism of ...
Giacomo Cassarà, María Gil‐Moles, Thomas Scattolin, M. Concepción Gimeno   +3 more
wiley   +1 more source

Relationship between bisphosphonate use and risks of recurrence and mortality among hormone receptor–positive and triple‐negative breast cancer patients

Cancer, Volume 132, Issue 16, 15 August 2026.
Abstract Background Bisphosphonates (BPs) are routinely used as an adjuvant therapy for breast cancer to reduce the risk of bone recurrences given their anti‐resorptive effects on bones and antitumor characteristics. However, there remains limited evidence regarding their utility across different subtypes. Methods In this population‐based cohort study,
Liuye Huang, Linda S. Cook, Mei‐Tzu C. Tang, David R. Doody, Ulrike Peters, Wei Sun, Jeroen R. Huyghe, Kathleen E. Malone, Christopher I. Li   +8 more
wiley   +1 more source

Triple-negative breast cancer: current understanding and future perspectives. [PDF]

Explor Target Antitumor Ther
Alobaidi A, Rai V.
europepmc   +1 more source

Globo‐H diagnostic stratification and identification of DUSP14 as a candidate target in colorectal cancer

International Journal of Cancer, Volume 159, Issue 4, Page 936-950, 15 August 2026.
What's new? Colorectal cancer (CRC) is increasingly complicated by drug‐resistant tumors that limit the effectiveness of anticancer therapies. Because resistance mechanisms vary among patients and can evolve over time, personalized treatment strategies are needed.
Keren Zohar, Marco Strecker, Thomas Wartmann, Wenjie Shi, Frederike Stelter, Maximilian Doelling, Mihailo Andric, Or Kakhlon, Christian Täger, Denny Schanze, Michael Linnebacher, Michael Naumann, Daniel E. Stange, Dörthe Jechorek, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Polyphyllin B induces ferroptosis in triple-negative breast cancer by inactivating NRF2. [PDF]

Front Pharmacol
Deng P, Zhu S, Wu Y, Fang Z, Zhang A, Zhang D, Hu X, Zhou X.   +7 more
europepmc   +1 more source

Exploring the Chemical Space Around Protoflavonoids: Synthesis and Antitumor Activity of Protochalcones

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Natural and synthetic protoflavonoids offer potent anticancer properties, but their chemical space remains largely unexplored. This study details the synthesis of eleven p‐hydroxydienone derivatives from chalcone precursors. We evaluated their antiproliferative effects across four human gynecological cancer cell lines.
Tímea Gonda, Kornél Szőri, Ahmed Dhahir Latif, Norbert Kúsz, János Soltész, István Zupkó, Erzsébet Mernyák, Attila Hunyadi   +7 more
wiley   +1 more source

Hemodynamic Inflow-Outflow Profiling as an Integrated DCE-MRI Biomarker for Diagnosis and Risk Stratification in Breast Cancer: A Multicenter Retrospective Study. [PDF]

Breast Cancer (Dove Med Press)
Zhou C, Guo Y, Meng Z, Wan K, Qin J, Wang Y.   +5 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, Volume 20, Issue 8, Page 1986-2007, August 2026.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source