M2 macrophages predict response to neoadjuvant chemotherapy in triple negative breast cancer patients. [PDF]
Chen WX +7 more
europepmc +1 more source
Garcinone C (Gar. C), a xanthone derived from mangosteen (Garcinia mangostana), suppresses triple‐negative breast cancer growth and stemness by inducing mitochondrial‐mediated apoptosis and inhibiting the Wnt/β‐catenin pathway, highlighting its potential as a natural compound for the prevention and treatment TNBC.
Danhong Zheng +4 more
wiley +1 more source
Metformin drives HIF-1α-mediated dual metabolic reprogramming to enhance γδ T cell therapy in triple-negative breast cancer. [PDF]
Qin X +9 more
europepmc +1 more source
Synthesis, Characterization, and Cytotoxic Activity Properties of Some Novel Purine Derivatives
Nine novel purine derivatives were successfully synthesized and its cytotoxic activities were evaluated against HepG2 and MDA‐MB‐231 cancer cell lines. ABSTRACT This study reports the synthesis of nine new compounds with purine scaffolds. It thoroughly analyzes them using a variety of spectroscopic methods, including high‐resolution mass spectrometry ...
Nurdan Akdoğan +6 more
wiley +1 more source
Discrimination of Triple-Negative Breast Cancer: A Robust Clinical Baseline versus Multimodal Magnetic Resonance Imaging Integrated Models with Assessment of Generalizability. [PDF]
Liao X, Wu X, Zheng J, Lin G, Lin D.
europepmc +1 more source
ABSTRACT Introduction Pathological complete response (pCR) after neoadjuvant chemotherapy is associated with improved prognosis in patients with triple‐negative breast cancer (TNBC). Differences in pathological response rates between the breast and axillary lymph nodes have prompted interest in understanding response patterns that may, in the future ...
Milena Martello Cristófalo +7 more
wiley +1 more source
Integrated single-cell and spatial mapping coupled with machine learning unveils core stemness landscapes and regulatory drivers in triple-negative breast cancer. [PDF]
Huo Z, Sun W, Lou C, Yang T.
europepmc +1 more source
RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Decoding the Clinical and Therapeutic Significance of MEAK7 in Triple-Negative Breast Cancer Through Integrative Bioinformatics. [PDF]
Ayan D, Kan MU, Bayram E, Soylemez S.
europepmc +1 more source
Opioids in breast cancer: Between analgesia and modulation of tumour progression
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun +2 more
wiley +1 more source

