Results 211 to 220 of about 82,941 (302)

HDHD5 promotes triple-negative breast cancer growth and drives EMT-associated phenotypes via regulating S100A4. [PDF]

J Cancer Res Clin Oncol
Cai JY, Zhang YL, Zhang FL, Zhao Q, Ma MK, Shao ZM.   +5 more
europepmc   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak, Noor Hussein, Veronica Piedra, Saloni Malla, Chandrabose Karthikeyan, Haneen Amawi, Harish Rajak, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +9 more
wiley   +1 more source

AI-mediated ultrasound radiomics in the diagnosis and treatment of triple-negative breast cancer: research progress and future challenges. [PDF]

Front Oncol
Wang Z, Wang Y, Yu T, Yi Y, Xue K, Xu W.
europepmc   +1 more source

CD133 Shapes Extracellular Vesicle Cargo and Angiogenic Function in Basal‐Like Triple‐Negative Breast Cancer

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are central mediators of tumour‐stroma communication, yet the mechanisms governing their biogenesis and functional cargo remain poorly understood. Here, we identify CD133 (Prominin‐1), selectively expressed in basal‐like triple‐negative breast cancer (BL‐TNBC) cells, acts as a key organizer of EV production and ...
Mireia Gomez‐Duro, Ptissam Bergam, Sara Sanchez‐Redondo, Florent Dingli, Alix Zhou, Alain Joliot, Mengliang Ye, Marta Hergueta‐Redondo, Lucas Alves Tavares, Damarys Loew, Thierry Dubois, Lorena Martin‐Jaular, Hector Peinado, Graça Raposo, Gisela D'Angelo   +14 more
wiley   +1 more source

Effects of SOX10 on the proliferative, invasive, migratory, and epithelial-mesenchymal transition abilities of triple-negative breast cancer cells. [PDF]

Front Oncol
Wang S, Jin L.
europepmc   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

LncRNAs as regulators of chemoresistance and chemosensitivity in triple-negative breast cancer. [PDF]

Genet Mol Biol
Cáceres-Durán MÁ, Rodrigues ACL, Azevedo Junior JC, Alves CD, Calcagno DQ, Borges BDN.   +5 more
europepmc   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source