Assessment of IL6 and TNF α in Chronic Lymphocytic Leukemia [PDF]
Background: Among the cytokines and inflammatory markers, Interleukin 6 [IL6] and TNF α are the most common markers in the practice of medicine. Many studies determine the values of these two markers among the patients with chronic lymphocytic leukemia ...
Mohamed Abd-El-Haleem Mousa +3 more
doaj +1 more source
Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening. [PDF]
Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine important in normal and pathological biological processes. Newly synthesized pro-TNF-α is expressed on the plasma membrane and cleaved to release soluble TNF-α protein: both are ...
Sutthirat Udommethaporn +3 more
doaj +1 more source
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine involved in the pathogenesis of sarcopenia, but its short half-life and inconsistent reproducibility limit the potential of TNF-α to be an ideal sarcopenia biomarker.
Wei-Ju Lin +7 more
doaj +1 more source
Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B [PDF]
Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-I² and TNF-I ...
Ahmad Taha Khalaf, Yan Yuehua
openaire +1 more source
Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism. [PDF]
Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression is up-regulated in chronic obstructive pulmonary disease (COPD).
Xue-Ke Zhao +20 more
doaj +1 more source
Correlation of Serum Interleukin-6, TNF-α, Procalcitonin and Leukocyte Count in Patients with Suspected Sepsis [PDF]
Sepsis is a cause of non-cardiac death in the hospital. Early and rapid diagnosis of septic patients is a challenge toincrease the expectancy of life. IL-6 and TNF-α are groups of pro inflammatory cytokines that initiate an initial inflammatoryresponse. Procalcitonin is a specific marker of bacterial infection.
Erfina Lim, Jusak Nugraha
openaire +1 more source
Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells. [PDF]
Tumor necrosis factor (TNF)-α, which is a mediator of hepatotoxicity, has been implicated in liver fibrosis. However, the roles of TNF-α on hepatic stellate cell (HSC) activation and liver fibrosis are complicated and remain controversial.
Yosuke Osawa +5 more
doaj +1 more source
Background: Psoriasis vulgaris is a recurrent chronic skin disorder signed by hyperproliferation and epidermal inflammation. One of the etiology of psoriasis is genetic factors related to genetic polymorphism as disease susceptibility markers. This study was aimed to analyze the correlation of TNF-α gene promoter region polymorphism with psoriasis ...
Cashtri Meher +2 more
openaire +1 more source
Correlation Between TNF- α and Degree of Gastritis
Background: TNF- α is a cytokine that plays an active role in the pathogenesis of gastritis. The correlation of TNF-α levels in the gastric mucosa with the severity of gastritis has long been known.
Ricky Rivalino +2 more
doaj +1 more source
Pulmonary artery perfusion with anti-tumor necrosis factor alpha antibody reduces cardiopulmonary bypass-induced inflammatory lung injury in a rabbit model. [PDF]
Inflammatory lung injury is one of the main complications associated with cardiopulmonary bypass (CPB). Tumor necrosis factor-α (TNF-α) is one of the key factors mediating the CPB-induced inflammatory reactions.
Yang Yu +4 more
doaj +1 more source

