Results 111 to 120 of about 565,658 (299)
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang +13 more
wiley +1 more source
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava +7 more
wiley +1 more source
TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice
Background/Aims: Obese patients and experimental animals exhibit high levels of inflammatory cytokines, such as tumor necrosis factor (TNF)-α. However, the role of TNF-α in the pathophysiologic process in obesity induced kidney damage is still unknown ...
Huaiguo Wang +4 more
doaj +1 more source
Preterm condition gives a new stressful environment to infants. This condition needs a good and gradual adaptation. External environmental conditions, treatment, care and good nutrition are needed. Massage stimulation in preterm infants is a method that can prepare preterm infants’ adaptation through the critical post-birth period.
I G. A. Trisna-Windiani +3 more
openaire +1 more source
Transcriptional profiling of IKK2/NF-κB— and p38 MAP kinasedependent gene expression in TNF-α—stimulated primary human endothelial cells [PDF]
Dorothee Viemann +6 more
openalex +1 more source
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi +7 more
wiley +1 more source
TNF-α Compensates for the Impaired Host Defense of IL-1 Type I Receptor-Deficient Mice During Pneumococcal Pneumonia [PDF]
Anita W. Rijneveld +5 more
openalex +1 more source
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang +14 more
wiley +1 more source

