Results 51 to 60 of about 18,335 (201)

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

The Effects of Tocotrienol on Gut Microbiota: A Scoping Review [PDF]

Gut dysbiosis has been associated with many chronic diseases, such as obesity, inflammatory bowel disease, and cancer. Gut dysbiosis triggers these diseases through the activation of the immune system by the endotoxins produced by gut microbiota, which ...
Muhammad N, Hanafiah A, Pang KL, Wong SK, Kumareswaran A, Chin KY, Ekeuku SO, Mohamed N, Deborah Chia HC   +8 more
core   +4 more sources

Loss of Vitamin E While Baking and Heating French Fries

Applied Sciences, 2023
Vitamin E, as the most important lipophilic antioxidant of eukaryotic cells, plays an important role in human nutrition. So far, information has focused on the content of vitamin E in raw food materials or foods, and its losses under various processes ...
Vojtech Ilko, Dominika Sosnová, Petra Hrůšová, Jakub Fišnar, Štěpán Czornyj, Marek Doležal, Kristina Nakonechna, Zuzana Réblová   +7 more
doaj   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Effect of tocotrienol administration on reproductive efficiency and testicular tissue in obesity induced male rats [PDF]

Romanian Journal of Medical Practice
Obesity is a major public health problem for all age groups across the world. Diet, rather than hereditary alterations, is thought to have a significant role in the obesity pandemic.
Eman H. RAHI, Nameer A. KHUDHAIR
doaj   +1 more source

Serum Metabolomic Alteration in Rats with Osteoarthritis Treated with Palm Tocotrienol-Rich Fraction Alone or in Combination with Glucosamine Sulphate

Life, 2023
Osteoarthritis (OA) is a degenerative joint condition with limited disease-modifying treatments currently. Palm tocotrienol-rich fraction (TRF) has been previously shown to be effective against OA, but its mechanism of action remains elusive.
Sophia Ogechi Ekeuku, Jen-Kit Tan, Hiba Murtadha Al-Saadi, Fairus Ahmad, Mohd Ramli Elvy Suhana, Azlan Mohd Arlamsyah, Fadhlullah Zuhair Japar Sidik, Juliana Abdul Hamid, Soelaiman Ima-Nirwana, Kok-Yong Chin   +9 more
doaj   +1 more source

Tocotrienol as a potential anticancer agent [PDF]

Carcinogenesis, 2011
Vitamin E is composed of two structurally similar compounds: tocopherols (TPs) and tocotrienols (T3). Despite being overshadowed by TP over the past few decades, T3 is now considered to be a promising anticancer agent due to its potent effects against a wide range of cancers. A growing body of evidence suggests that in addition to its antioxidative and
Ling, Patrick, Luk, Sze Ue, Al-Ejeh, Fares, Khanna, Kum   +3 more
openaire   +6 more sources

Engineering endosperm storage compartments enables simultaneous enrichment of multiple vitamins in rice

Journal of Integrative Plant Biology, EarlyView.
Engineering rice endosperm with modules for vitamin binding, lipid storage, and antioxidant protection enriched water‐ and fat‐soluble vitamins without compromising key agronomic traits and maintained vitamin higher levels after cooking, demonstrating its potential to improve crop nutrition.
Xingwei Cai, Huanteng Hou, Yuanyue Wang, Wenyao Tan, Haifeng Zhu, Mustafa Bulut, Zhuang Yang, Ran Xu, Xianqing Liu, Alisdair R. Fernie, Jie Li, Yufei Li, Jie Luo   +12 more
wiley   +1 more source

Preventive Effects of Tocotrienol on Stress-Induced Gastric Mucosal Lesions and Its Relation to Oxidative and Inflammatory Biomarkers. [PDF]

PLoS ONE, 2015
This study aimed to investigate the possible gastroprotective effect of tocotrienol against water-immersion restraint stress (WIRS) induced gastric ulcers in rats by measuring its effect on gastric mucosal nitric oxide (NO), oxidative stress, and ...
Mohd Fahami Nur Azlina, Yusof Kamisah, Kien Hui Chua, Ibrahim Abdel Aziz Ibrahim, Hj Mohd Saad Qodriyah   +4 more
doaj   +1 more source

Diet‐Related Differences Predominate Over Breed‐Associated Differences in Hepatic Lipid Metabolism, Antioxidant Vitamins and Lipid Quality Indices Among Beef Cattle

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Understanding how nutritional management and genetic background influence hepatic metabolism is important for improving the nutritional quality of bovine products in tropical production systems. This study evaluated breed‐associated differences under a common dietary regimen and diet‐related differences within the Nelore breed with respect to ...
Laíza de Kássia Mendes da Conceição, José de Brito Lourenço‐Júnior, Jamile Andréa Rodrigues da Silva, Leonel António Joaquim, Mariana Jucá Moraes, Thomaz Cyro Guimarães de Carvalho Rodrigues, Joana Inês Ferreira, Ana Maria Ramos Fontes, Maria Pinheiro Spínola, Érica Coutinho David, Antônio Vinicius Correa Barbosa, Bruno Cabral Soares, José António Mestre Prates   +12 more
wiley   +1 more source