Results 31 to 40 of about 18,335 (201)

Co-solvent selection for tocotrienol extraction from palm fatty acid distillate using supercritical carbon dioxide

, 2022
A predictive model was devised for the estimation of the Kamlet-Taft (KT) dipolarity/polarisability (π*) parameter for binary mixtures of supercritical carbon dioxide (scCO2) and co-solvent.
Chong, Gun Hean, Suleiman, Norhidayah, Othman, Najwa, Mohamad Azman, Ezzat   +3 more
core   +1 more source

TOCOTRIENOL DEMONSTRA POTENTE ATIVIDADE ANTINEOPLÁSICA NO MICROAMBIENTE TUMORAL

Hematology, Transfusion and Cell Therapy, 2023
Objetivos: A leucemia mieloide aguda (LMA) é uma doença sistêmica que continua sendo um grave problema médico em todo o mundo. O acúmulo de células leucêmicas na medula óssea, leva a supressão da hematopoiese normal e promove processos inflamatórios que ...
MLP Bueno, I Santos, NG Amôr, ADS Santos, A Bastos, KP Ferro, STO Saad, FM Roversi   +7 more
doaj   +1 more source

δ-tocotrienol protects mouse and human hematopoietic progenitors from γ-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling

Haematologica, 2010
Background Exposure to γ-radiation causes rapid hematopoietic cell apoptosis and bone marrow suppression. However, there are no approved radiation countermeasures for the acute radiation syndrome. In this study, we demonstrated that natural δ-tocotrienol,
Xiang Hong Li, Dadin Fu, Nabil H. Latif, Conor P. Mullaney, Patrick H. Ney, Steven R. Mog, Mark H. Whitnall, Venkataraman Srinivasan, Mang Xiao   +8 more
doaj   +1 more source

Tocotrienol-Rich Tocomin Attenuates Oxidative Stress and Improves Endothelium-Dependent Relaxation in Aortae from Rats Fed a High-Fat Western Diet

, 2016
We have previously reported that tocomin, a mixture high in tocotrienol content and also containing tocopherol, acutely preserves endothelial function in the presence of oxidative stress.
Trisha A. Jenkins (3934424), Jason C. D. Nguyen (19075043), Owen L. Woodman (218513), Saher Ali (18943147)   +3 more
core   +2 more sources

Mechanisms Mediating the Effects of γ-Tocotrienol When Used in Combination with PPARγ Agonists or Antagonists on MCF-7 and MDA-MB-231 Breast Cancer Cells

International Journal of Breast Cancer, 2013
γ-Tocotrienol is a natural vitamin E that displays potent anticancer activity, and previous studies suggest that these effects involve alterations in PPARγ activity.
Abhita Malaviya, Paul W. Sylvester
doaj   +1 more source

δ-tocotrienol Inhibits Proliferation of Cervical Carcinoma Cells Through Upregulating MicroRNA-34a

Zhongliu Fangzhi Yanjiu, 2018
Objective To determine the effects of δ-tocotrienol on the proliferation of cervical carcinoma HeLa cells and whether miR-34a is involved in this process.
YU Ying, HUANG Jing, LI Rong, LIU Lianbin, WANG Qi, LUO Deping   +5 more
doaj   +1 more source

γ-Tocotrienol Inhibits Proliferation and Induces Apoptosis via the Mitochondrial Pathway in Human Cervical Cancer HeLa Cells

Molecules, 2017
γ-Tocotrienol, a kind of isoprenoid phytochemical, has antitumor activity. However, there is limited evidence that it has an effect on cervical cancer.
Weili Xu, Yaqing Mi, Pan He, Shenghua He, Lingling Niu   +4 more
doaj   +1 more source

Distribution of Tocotrienols in Rats Fed a Rice Bran Tocotrienol Concentrate

Bioscience, Biotechnology, and Biochemistry, 2007
To examine the distribution of rice bran tocotrienol (T3), we gave rice bran T3 to rats after considering an acceptable daily intake of vitamin E for humans. Male SD rats (5 weeks of age) were fed for 3 weeks on a commercial diet containing 6.4 mg of vitamin E per 100 g wt and additively received vitamin E or the vehicle (vitamin E-free corn oil) by ...
KAWAKAMI, Yuki, TSUZUKI, Tsuyoshi, NAKAGAWA, Kiyotaka, MIYAZAWA, Teruo   +3 more
openaire   +2 more sources

Synergistic Antiproliferative Effects of Combined γ-Tocotrienol and PPARγ Antagonist Treatment Are Mediated through PPARγ-Independent Mechanisms in Breast Cancer Cells

PPAR Research, 2014
Previous findings showed that the anticancer effects of combined γ-tocotrienol and peroxisome proliferator activated receptor γ (PPARγ) antagonist treatment caused a large reduction in PPARγ expression.
Abhita Malaviya, Paul W. Sylvester
doaj   +1 more source

Potentiation of in vitro apoptotic effects of δ-Tocotrienol and Jerantinine A on human lung adenocarcinoma cells [PDF]

Journal of HerbMed Pharmacology, 2019
Introduction: The apoptotic effects of single-compound and combined sub-effective concentrations of δ-tocotrienol and jerantinine A on human lung adenocarcinoma (A549) cells were investigated.
Ibrahim Babangida Abubakar, Hwei-San Loh
doaj   +1 more source