Results 21 to 30 of about 18,335 (201)

Delivery of the vitamin E compound tocotrienol to cancer cells [PDF]

open access: yes, 2011
Tocotrienol, a member of the vitamin E family of compounds, is currently receiving increased attention because of its highly promising anti-cancer effects.
Dufès, Christine
core   +3 more sources

Efficacy of Vitamin E Administration on Serum Lipid Profile in Adult Patients With Dyslipidemia: A GRADE‐Assessed Systematic Review and Dose–Response Meta‐Analysis of RCTs [PDF]

open access: yesFood Sci Nutr
The graphical abstract summarizes a GRADE‐assessed systematic review and dose–response meta‐analysis of 22 randomized controlled trials evaluating oral vitamin E supplementation in adults with dyslipidemia. It presents the effects on serum lipid parameters, including triglycerides (TG), total cholesterol (TC), LDL‐C, and HDL‐C.
Karimi M   +7 more
europepmc   +2 more sources

A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women: safety, quality of life, body composition, physical activity, and nutrient intake

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety in this population has never been investigated.
Chwan-Li Shen   +10 more
doaj   +1 more source

γ-Tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor

open access: yesJournal of Lipid Research, 2003
2,7,8-Trimethyl-2-(β-carboxyethyl)-6-hydroxychroman (γ-CEHC), a metabolite of γ-tocopherol and γ-tocotrienol, was identified as a new endogenous natriuretic factor.
Hisako Saito   +5 more
doaj   +1 more source

Tocotrienol as a Protecting Agent against Glucocorticoid-Induced Osteoporosis: A Mini Review of Potential Mechanisms

open access: yesMolecules, 2022
Glucocorticoid-induced osteogenic dysfunction is the main pathologyical mechanism underlying the development of glucocorticoid-induced osteoporosis. Glucocorticoids promote adipogenic differentiation and osteoblast apoptosis through various pathways ...
Sophia Ogechi Ekeuku   +5 more
doaj   +1 more source

Tocotrienols: inflammation and cancer [PDF]

open access: yesAnnals of the New York Academy of Sciences, 2011
Inflammation is an organism's response to environmental assaults. It can be classified as acute inflammation that leads to therapeutic recovery or chronic inflammation, which may lead to the development of cancer and other ailments. Genetic changes that occur within cancer cells themselves are responsible for many aspects of cancer development but are ...
Kalanithi, Nesaretnam   +1 more
openaire   +2 more sources

Impact of delta-tocotrienol on human melanoma cell proliferation [PDF]

open access: yes, 2010
The rate-limiting enzyme of the mevalonate pathway, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, provides essential intermediates for the prenylation or dolichylation of growth-related proteins including nuclear Ras, nuclear lamins, and ...
Fernandes, Nicolle Valerie
core   +4 more sources

Strategies to Enhance the Solubility and Bioavailability of Tocotrienols Using Self-Emulsifying Drug Delivery System

open access: yesPharmaceuticals, 2023
Tocotrienols have higher medicinal value, with multiple sources of evidence showing their biological properties as antioxidant, anti-inflammatory, and osteoprotective compounds.
Nur-Vaizura Mohamad
doaj   +1 more source

Characterization of Powdered Roasted Açaí Seeds (Euterpe oleracea Mart.): Impact on Bioactive Compounds and Nutritional Potential [PDF]

open access: yesFood Sci Nutr
Roasting enhanced the functional potential of açaí (Euterpe oleracea Mart.) seeds, yielding a fiber‐rich powder with relevant minerals and bioactive compounds. Both lipid and aqueous extracts showed high phenolic contents and antioxidant activity, while the lipid fraction provided vitamin E‐active compounds and valuable fatty acids.
da Silva Magalhães R   +9 more
europepmc   +2 more sources

The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocin-induced diabetic rats

open access: yesClinics, 2009
OBJECTIVE: This study examined the effects of palm oil tocotrienol-rich fractions on streptozotocin-induced diabetic rats. METHODS: Animals were divided into three groups: (i) normal non-diabetic (NDM), (ii) diabetic treated (tocotrienol-rich fractions -
Siti Balkis Budin   +5 more
doaj   +1 more source

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