Results 21 to 30 of about 17,882 (203)

Delivery of the vitamin E compound tocotrienol to cancer cells [PDF]

open access: yes, 2011
Tocotrienol, a member of the vitamin E family of compounds, is currently receiving increased attention because of its highly promising anti-cancer effects.
Dufès, Christine
core   +3 more sources

A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women: safety, quality of life, body composition, physical activity, and nutrient intake

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety in this population has never been investigated.
Chwan-Li Shen   +10 more
doaj   +1 more source

γ-Tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor

open access: yesJournal of Lipid Research, 2003
2,7,8-Trimethyl-2-(β-carboxyethyl)-6-hydroxychroman (γ-CEHC), a metabolite of γ-tocopherol and γ-tocotrienol, was identified as a new endogenous natriuretic factor.
Hisako Saito   +5 more
doaj   +1 more source

Tocotrienols: inflammation and cancer [PDF]

open access: yesAnnals of the New York Academy of Sciences, 2011
Inflammation is an organism's response to environmental assaults. It can be classified as acute inflammation that leads to therapeutic recovery or chronic inflammation, which may lead to the development of cancer and other ailments. Genetic changes that occur within cancer cells themselves are responsible for many aspects of cancer development but are ...
Kalanithi, Nesaretnam   +1 more
openaire   +2 more sources

Impact of delta-tocotrienol on human melanoma cell proliferation [PDF]

open access: yes, 2010
The rate-limiting enzyme of the mevalonate pathway, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, provides essential intermediates for the prenylation or dolichylation of growth-related proteins including nuclear Ras, nuclear lamins, and ...
Fernandes, Nicolle Valerie
core   +4 more sources

The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocin-induced diabetic rats

open access: yesClinics, 2009
OBJECTIVE: This study examined the effects of palm oil tocotrienol-rich fractions on streptozotocin-induced diabetic rats. METHODS: Animals were divided into three groups: (i) normal non-diabetic (NDM), (ii) diabetic treated (tocotrienol-rich fractions -
Siti Balkis Budin   +5 more
doaj   +1 more source

Strategies to Enhance the Solubility and Bioavailability of Tocotrienols Using Self-Emulsifying Drug Delivery System

open access: yesPharmaceuticals, 2023
Tocotrienols have higher medicinal value, with multiple sources of evidence showing their biological properties as antioxidant, anti-inflammatory, and osteoprotective compounds.
Nur-Vaizura Mohamad
doaj   +1 more source

Co-solvent selection for tocotrienol extraction from palm fatty acid distillate using supercritical carbon dioxide

open access: yes, 2022
A predictive model was devised for the estimation of the Kamlet-Taft (KT) dipolarity/polarisability (π*) parameter for binary mixtures of supercritical carbon dioxide (scCO2) and co-solvent.
Chong, Gun Hean   +3 more
core   +1 more source

TOCOTRIENOL DEMONSTRA POTENTE ATIVIDADE ANTINEOPLÁSICA NO MICROAMBIENTE TUMORAL

open access: yesHematology, Transfusion and Cell Therapy, 2023
Objetivos: A leucemia mieloide aguda (LMA) é uma doença sistêmica que continua sendo um grave problema médico em todo o mundo. O acúmulo de células leucêmicas na medula óssea, leva a supressão da hematopoiese normal e promove processos inflamatórios que ...
MLP Bueno   +7 more
doaj   +1 more source

δ-tocotrienol protects mouse and human hematopoietic progenitors from γ-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling

open access: yesHaematologica, 2010
Background Exposure to γ-radiation causes rapid hematopoietic cell apoptosis and bone marrow suppression. However, there are no approved radiation countermeasures for the acute radiation syndrome. In this study, we demonstrated that natural δ-tocotrienol,
Xiang Hong Li   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy