Results 11 to 20 of about 22,121 (219)

γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. [PDF]

open access: yesPLoS ONE, 2013
Colorectal cancer is one of the most serious illnesses among diagnosed cancer. As a new type of anti-cancer composition from tocotrienol-rich fraction of palm oil, γ-tocotrienol is widely used in anti-cancer research. The objectives of this study were to
Jing-Shu Zhang   +8 more
doaj   +4 more sources

The Role of Tocotrienol in Protecting Against Metabolic Diseases [PDF]

open access: yesMolecules, 2019
Obesity is a major risk factor for diabetes, and these two metabolic conditions cause significant healthcare burden worldwide. Chronic inflammation and increased oxidative stress due to exposure of cells to excess nutrients in obesity may trigger insulin
Kok-Lun Pang, Kok-Yong Chin
doaj   +3 more sources

Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. [PDF]

open access: yesPLoS ONE, 2013
Vitamin E δ-tocotrienol has been shown to have antitumor activity, but the precise molecular mechanism by which it inhibits the proliferation of cancer cells remains unclear.
Pamela J Hodul   +11 more
doaj   +1 more source

The Role of Tocotrienol in Arthritis Management—A Scoping Review of Literature

open access: yesPharmaceuticals, 2023
Arthritis is a cluster of diseases impacting joint health and causing immobility and morbidity in the elderly. Among the various forms of arthritis, osteoarthritis (OA) and rheumatoid arthritis (RA) are the most common.
Hashwin Singh Tejpal Singh   +4 more
doaj   +1 more source

Transcriptomic Analysis of the Anticancer Effects of Annatto Tocotrienol, Delta-Tocotrienol and Gamma-Tocotrienol on Chondrosarcoma Cells

open access: yesNutrients, 2022
Previous studies have demonstrated the anticancer activities of tocotrienol on several types of cancer, but its effects on chondrosarcoma have never been investigated. Therefore, this study aims to determine the anticancer properties of annatto tocotrienol (AnTT), γ-tocotrienol (γ-T3) and δ-tocotrienol (δ-T3) on human chondrosarcoma SW1353 cells ...
Kok-Lun Pang   +6 more
openaire   +2 more sources

Experimental feasibility study of using date palm oil as a bitumen Bio-Modifier in HMA pavement [PDF]

open access: yes, 2020
This paper examines the effects of Date palm oil as a bitumen modifier on the compressive strength of bitumen and hot mixed asphalt (HMA) pavement.
Abu Yousef, Mohammad, Amin, Shohel
core   +2 more sources

Tocotrienols: inflammation and cancer [PDF]

open access: yesAnnals of the New York Academy of Sciences, 2011
Inflammation is an organism's response to environmental assaults. It can be classified as acute inflammation that leads to therapeutic recovery or chronic inflammation, which may lead to the development of cancer and other ailments. Genetic changes that occur within cancer cells themselves are responsible for many aspects of cancer development but are ...
Kalanithi, Nesaretnam   +1 more
openaire   +2 more sources

A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women: safety, quality of life, body composition, physical activity, and nutrient intake

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety in this population has never been investigated.
Chwan-Li Shen   +10 more
doaj   +1 more source

The Effects of Tocotrienol on Gut Microbiota: A Scoping Review

open access: yesLife, 2023
Gut dysbiosis has been associated with many chronic diseases, such as obesity, inflammatory bowel disease, and cancer. Gut dysbiosis triggers these diseases through the activation of the immune system by the endotoxins produced by gut microbiota, which ...
Aswini Kumareswaran   +8 more
doaj   +1 more source

γ-Tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor

open access: yesJournal of Lipid Research, 2003
2,7,8-Trimethyl-2-(β-carboxyethyl)-6-hydroxychroman (γ-CEHC), a metabolite of γ-tocopherol and γ-tocotrienol, was identified as a new endogenous natriuretic factor.
Hisako Saito   +5 more
doaj   +1 more source

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