Results 11 to 20 of about 17,882 (203)
Nutrients, 2022 Previous studies have demonstrated the anticancer activities of tocotrienol on several types of cancer, but its effects on chondrosarcoma have never been investigated. Therefore, this study aims to determine the anticancer properties of annatto tocotrienol (AnTT), γ-tocotrienol (γ-T3) and δ-tocotrienol (δ-T3) on human chondrosarcoma SW1353 cells ...
Kok-Lun Pang +6 more
openaire +3 more sources
The Role of Tocotrienol in Protecting Against Metabolic Diseases [PDF]
Molecules, 2019 Obesity is a major risk factor for diabetes, and these two metabolic conditions cause significant healthcare burden worldwide. Chronic inflammation and increased oxidative stress due to exposure of cells to excess nutrients in obesity may trigger insulin
Kok-Lun Pang, Kok-Yong Chin
doaj +2 more sources
The Effects of Tocotrienol on Gut Microbiota: A Scoping Review
Life, 2023 Gut dysbiosis has been associated with many chronic diseases, such as obesity, inflammatory bowel disease, and cancer. Gut dysbiosis triggers these diseases through the activation of the immune system by the endotoxins produced by gut microbiota, which ...
Aswini Kumareswaran +8 more
doaj +2 more sources
γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. [PDF]
PLoS ONE, 2013 Colorectal cancer is one of the most serious illnesses among diagnosed cancer. As a new type of anti-cancer composition from tocotrienol-rich fraction of palm oil, γ-tocotrienol is widely used in anti-cancer research. The objectives of this study were to
Jing-Shu Zhang +8 more
doaj +2 more sources
Gamma-Tocotrienol Stimulates the Proliferation, Differentiation, and Mineralization in Osteoblastic MC3T3-E1 Cells [PDF]
Journal of Chemistry, 2018 Gamma-tocotrienol, a major component of tocotrienol-rich fraction of palm oil, has been suggested to exhibit bone protective effects in vivo. However, the effects of γ-tocotrienol on osteoblast cells are still unclear.
Weili Xu +7 more
doaj +2 more sources
Tocotrienol supplementation in postmenopausal osteoporosis: evidence from a laboratory study
Clinics, 2013 OBJECTIVE: Accelerated bone loss that occurs in postmenopausal women has been linked to oxidative stress and increased free radicals. We propose the use of antioxidants to prevent and reverse postmenopausal osteoporosis.
Norliza Muhammad +4 more
doaj +2 more sources
The biological effects of tocotrienol on bone: a review on evidence from rodent models
Drug Design, Development and Therapy, 2015 Kok-Yong Chin, Soelaiman Ima-Nirwana Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia Abstract: Osteoporosis causes significant health care and economic burden to society, leading to
Chin KY, Ima-Nirwana S
doaj +1 more source
Tocotrienol in the Treatment of Topical Wounds: Recent Updates
Pharmaceutics, 2022 Healing wounds is an important attempt to keep the internal higher organs safe. Complications in topical wound healing may lead to the formation of scars, which can affect the patient’s quality of life. Although several approaches are ongoing in parallel
Anroop B. Nair +8 more
doaj +2 more sources
Drug Design, Development and Therapy, 2018 Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana, Kok-Yong Chin Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Background: Patients receiving androgen deprivation therapy experience secondary ...
Mohamad NV, Ima-Nirwana S, Chin KY
doaj +1 more source
The Professional Medical Journal, 2012 Objective: To evaluate the effect of tocotrienols on intimal thickening in ascending aorta of cholesterol-fed rabbits. StudyDesign: Randomized control trial. Place and duration of study: The Anatomy department of Army Medical College, Rawalpindi, from March2009 to February 2010.
Uzma SHAHID +2 more
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