Results 31 to 40 of about 15,995 (210)
BINDING OF TOLBUTAMIDE TO GLYCATED HUMAN SERUM ALBUMIN [PDF]
, 2011 The presence of elevated levels of glucose in blood during diabetes can lead to the non-enzymatic glycation of serum proteins such as human serum albumin (HSA). This study examined the changes that occur in binding of the sulfonylurea drug tolbutamide to
David S. Hage +5 more
core +1 more source
Scientific Reports, 2017 The suprachiasmatic nucleus (SCN) central clock comprises two coupled oscillators, with light entraining the retinorecipient vasoactive intestinal peptide (VIP)-positive ventrolateral oscillator, which then entrains the arginine vasopressin (AVP ...
Jyh-Jeen Yang +4 more
doaj +1 more source
Effect of tolbutamide on plasma renin activity.
, 1979 The effect of tolbutamide on renin secretion in rats was studied in vivo, and in vitro. Administration of tolbutamide in doses of 12.5 and 25 mg/kg body wt ip to two groups of rats produced no significant change in plasma renin activity compared to the ...
N K Sherma +3 more
core +1 more source
Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations
Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera +2 more
wiley +2 more sources
Acta Pharmaceutica Sinica B, 2022 Sulfonylureas are widely used oral anti-diabetic drugs. However, its long-term usage effects on patients’ lifespan remain controversial, with no reports of influence on animal longevity.
Zhifan Mao +8 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2005 We examined the effect of several K+ channel blockers such as glibenclamide, tolbutamide, charybdotoxin (ChTX), apamin, tetraethylammonium chloride (TEA), 4-aminopyridine (4-AP), and cesium on the ability of fentanyl, a clinically used selective µ-opioid
A.R.A. Rodrigues +4 more
doaj +1 more source
Evaluation of lentinan effects on cytochrome P450 activity in rats by a cocktail method [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo.
Yiping Lin +8 more
doaj +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Biopharmaceutics &Drug Disposition, EarlyView.Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula +4 more
wiley +1 more source
Hypoglycaemic agents: variants of tolbutamide
, 1964 Further new variants of tolbutamide (and two new imidazolines) are described.
V Petrow +4 more
core +1 more source