Results 61 to 70 of about 2,394,994 (228)

Host genotype-specific rhizosphere fungus enhances drought resistance in wheat

Microbiome
Background The severity and frequency of drought are expected to increase substantially in the coming century and dramatically reduce crop yields.
Hong Yue, Xuming Sun, Tingting Wang, Ali Zhang, Dejun Han, Gehong Wei, Weining Song, Duntao Shu   +7 more
doaj   +1 more source

Algorithmic Based Fault Tolerance Applied to High Performance Computing

, 2008
We present a new approach to fault tolerance for High Performance Computing system. Our approach is based on a careful adaptation of the Algorithmic Based Fault Tolerance technique (Huang and Abraham, 1984) to the need of parallel distributed computation.
Bosilca, George, Delmas, Remi, Dongarra, Jack, Langou, Julien   +3 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Evaluation of a new method for quantification of heat tolerance in different wheat cultivars

Journal of Integrative Agriculture, 2018
Heat stress seriously affects wheat production in many regions of the world. At present, heat tolerance research remains one of the least understood fields in wheat genetics and breeding and there is a lack of effective methods to quantify heat stress ...
Qiang LI, Zheng-rui WANG, Ding LI, Jian-wei WEI, Wen-chen QIAO, Xiang-hai MENG, Shu-luan SUN, Hui-min LI, Ming-hui ZHAO, Xiu-min CHEN, Feng-wu ZHAO   +10 more
doaj   +1 more source

Effect of salinity on Arabidopsis thaliana seed germination and acid phosphatase activity [PDF]

Archives of Biological Sciences, 2016
The salt tolerance of four accessions of Arabidopsis thaliana (COL (Columbia), NOK2, N1438 and N1380) was evaluated during germination by the capacity of seeds to germinate in the presence of 50 mM NaCl and to maintain adequate acid phosphatase ...
Nasri Nawel, Maatallah Samira, Kaddour Rym, Lachâal Mokhtar   +3 more
doaj   +1 more source

The effects of changing climate on faunal depth distributions determine winners and losers

, 2014
Changing climate is predicted to impact all depths of the global oceans, yet projections of range shifts in marine faunal distributions in response to changing climate seldom evaluate potential shifts in depth distribution.
Airriess, Anttila, Barve, Bijima, Bograd, Brewer, Brown, Brown, Burrows, Burrows, Campenot, Cheung, Clark, Collins, Cottin, Dulvy, Frederich, George, Gibbs, Hönisch, Jackson, Keeling, Kroeker, Li, Lodish, Matear, McClain, Menzies, Mestre, Mickel, Mickel, Munday, Nye, Oliphant, Perry, Pinksy, Poloczanska, Pörtner, Pörtner, Pörtner, Pörtner, Schmittner, Shaffer, Smith, Soberón, Somero, Somero, Stillman, Storch, Stramma, Sunday, Thatje, Thatje, Tillman, Vaquer-Sunyer, Walther, Warrant, Whitney, Williams, Yasuhara   +59 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source