Results 81 to 90 of about 4,498,564 (240)
Cancer Medicine, 2022 Objective We aim to review the roles of plasmacytoid dendritic cells (pDCs) in head and neck squamous cell carcinoma (HNSCC) and explore the effects of hypoxia on the tolerogenic transformation of pDCs.
Cui Fan +7 more
doaj +1 more source
Therapeutic dendritic cell vaccination against human papillomavirus [PDF]
, 2009 Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually.
Nurkkala Karlsson, Merja
core +1 more source
Tolerogenic Dendritic Cells: All Present and Correct? [PDF]
American Journal of Transplantation, 2010 Although well-recognized for their sentinel role and, when activated, their immunostimulatory function, bone marrow-derived dendritic cells (DC) possess inherent tolerogenic (tol) ability. Under quiescent conditions, these cells maintain central and peripheral self tolerance.
openaire +2 more sources
Advanced Science, EarlyView.Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi +2 more
wiley +1 more source
The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance
Clinical and Developmental Immunology, 2011 Tumor cells commonly escape from elimination by innate and adaptive immune responses using multiple strategies among which is the active suppression of effector immune cells.
Nona Janikashvili +3 more
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Induction of Tolerogenic Dendritic Cells by Endogenous Biomolecules: An Update
Frontiers in Immunology, 2018 The importance of microenvironment on dendritic cell (DC) function and development has been strongly established during the last two decades. Although DCs with general tolerogenic characteristics have been isolated and defined as a particular sub ...
Urban Švajger +2 more
doaj +1 more source
Tolerogenic dendritic cells and their potential applications [PDF]
Immunology, 2011 Dendritic cells (DCs) play a pivotal role in regulating the balance between immunity and tolerance of the immune system. Recent advancements in DC biology and techniques for manipulating the function of these cells have shown their immense therapeutic potential for treating a variety of immune disorders.
Jim, Hu, Yonghong, Wan
openaire +2 more sources
Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Cell Communication and SignalingBackground Restoring impaired peripheral immune tolerance is the primary challenge in treating autoimmune diseases. Our previous research demonstrated the effectiveness of small spleen peptides (SSPs), a fraction of low molecular weight proteins, in ...
Viktor Wixler +4 more
doaj +1 more source
Advances in understanding of dendritic cell in the pathogenesis of acute kidney injury
Frontiers in ImmunologyAcute kidney injury (AKI) is characterized by a rapid decline in renal function and is associated with a high morbidity and mortality rate. At present, the underlying mechanisms of AKI remain incompletely understood.
Dongfang Lv +8 more
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