Results 261 to 270 of about 238,767 (310)
Possible involvement of Toll-like receptor 8-positive monocytes/macrophages in the pathogenesis of Sjögren's disease. [PDF]
Front ImmunolYan L +13 more
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miR-574-5p in epigenetic regulation and Toll-like receptor signaling. [PDF]
Cell Commun SignalYang JY.
europepmc +1 more source
Micellization of Lipopeptides Containing Toll-like Receptor Agonist and Integrin Binding Sequences. [PDF]
ACS Appl Mater InterfacesCastelletto V +3 more
europepmc +1 more source
Acid sphingomyelinase modulates anxiety-like behavior likely through toll-like receptor signaling pathway. [PDF]
Mol BrainYuan H +7 more
europepmc +1 more source
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Journal of biological regulators and homeostatic agents, 2008
Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading microbes by the immune system. As part of the innate immune system, Toll-like receptors recognise pathogen-associated molecular patterns, highly conserved components that are essential to microbial function.
Dasari, Pallave +2 more
+6 more sources
Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading microbes by the immune system. As part of the innate immune system, Toll-like receptors recognise pathogen-associated molecular patterns, highly conserved components that are essential to microbial function.
Dasari, Pallave +2 more
+6 more sources
Critical Care Medicine, 2002
The ability of a host to sense invasion by pathogenic organisms and to respond appropriately to control infection is paramount to survival. In the case of sepsis and septic shock, however, an exaggerated systemic response may, in fact, contribute to the morbidity and mortality associated with overwhelming infections.
Egil Lien, Robin R. Ingalls
openaire +4 more sources
The ability of a host to sense invasion by pathogenic organisms and to respond appropriately to control infection is paramount to survival. In the case of sepsis and septic shock, however, an exaggerated systemic response may, in fact, contribute to the morbidity and mortality associated with overwhelming infections.
Egil Lien, Robin R. Ingalls
openaire +4 more sources
Current Protocols in Immunology, 2007
AbstractThe mammalian Toll‐like receptor (TLR) family consists of 13 members, and recognizes specific patterns of microbial components, called pathogen‐associated molecular patterns (PAMPs). TLR‐dependent recognition of PAMPs leads to activation of the innate immune system, which subsequently leads to activation of antigen‐specific adaptive immunity ...
Shizuo Akira, Kiyoshi Takeda
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AbstractThe mammalian Toll‐like receptor (TLR) family consists of 13 members, and recognizes specific patterns of microbial components, called pathogen‐associated molecular patterns (PAMPs). TLR‐dependent recognition of PAMPs leads to activation of the innate immune system, which subsequently leads to activation of antigen‐specific adaptive immunity ...
Shizuo Akira, Kiyoshi Takeda
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, 2009 Since the discovery of toll-like receptors (TLRs) in Drosophila in 1996 [1], scientific knowledge has exploded on the role of pattern recognition receptors in immunity, host defense, and in various noninfectious conditions including liver diseases.
Szabo, Gyongyi, Mandrekar, Pranoti
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Journal of the European Academy of Dermatology and Venereology, 2011
AbstractToll‐like receptors are important pattern recognition receptors which have key roles in both innate and adaptive immune responses. They are strongly associated with the pathogenesis of inflammatory and autoimmune diseases. Furthermore, Toll‐like receptors have also been implicated in the pathogenesis of several skin diseases such as skin ...
Gunduz, K. +2 more
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AbstractToll‐like receptors are important pattern recognition receptors which have key roles in both innate and adaptive immune responses. They are strongly associated with the pathogenesis of inflammatory and autoimmune diseases. Furthermore, Toll‐like receptors have also been implicated in the pathogenesis of several skin diseases such as skin ...
Gunduz, K. +2 more
openaire +3 more sources
2014
This chapter focuses on examples of Toll-like receptors (TLRs) research where questions have been particularly well addressed as potential paradigms for the entire TLR system. Lipopolysaccharide (LPS) has been used for decades in immunology laboratories because of its multiple effects on innate immune cells as well as B lymphocytes and, after discovery
Natsuko Tanimura, Kensuke Miyake
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This chapter focuses on examples of Toll-like receptors (TLRs) research where questions have been particularly well addressed as potential paradigms for the entire TLR system. Lipopolysaccharide (LPS) has been used for decades in immunology laboratories because of its multiple effects on innate immune cells as well as B lymphocytes and, after discovery
Natsuko Tanimura, Kensuke Miyake
openaire +3 more sources