Results 61 to 70 of about 393,653 (192)

Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts [PDF]

, 2015
Surgical attenuation of a congenital portosystemic shunt (CPSS) results in increased portal vein perfusion, liver growth and clinical improvement. Portal lipopolysaccharide (LPS) is implicated in liver regeneration via toll-like receptor (TLR) 4 mediated
House, A K, Lipscomb, V J, Smith, K C, Tivers, M S, Wheeler-Jones, C P D   +4 more
core   +4 more sources

Toll-like receptors

British Journal of Medicine and Medical Research, 2013
The study results of the last 10-12 years have established that the activity of the nonspecific immunological protection system is based on a limited set of specific membrane receptors, which have been called molecular ‘pattern recognition receptors’ PRRs that recognize pathogen associated molecular patterns PAMPs.
Sardari, V.V., Vremere, N., Tagadiuc, O.C.   +2 more
openaire   +3 more sources

Influence of lipopolysaccharide on proinflammatory gene expression in human corneal, conjunctival and meibomian gland epithelial cells [PDF]

, 2018
PURPOSE: Lipopolysaccharide (LPS), a bacterial endotoxin, is known to stimulate leuokotriene B4 (LTB4) secretion by human corneal (HCECs), conjunctival (HConjECs) and meibomian gland (HMGECs) epithelial cells.
Chen, Di, Darabad, Raheleh Rahimi, Kam, Wendy R., Liu, Yang, Sahin, Afsun, Sullivan, David A.   +5 more
core   +1 more source

Placental Toll-like receptor 3 and Toll-like receptor 7/8 activation contributes to preeclampsia in humans and mice. [PDF]

PLoS ONE, 2012
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal immune system activation, inflammation, and endothelial dysfunction.
Piyali Chatterjee, Laura E Weaver, Karen M Doersch, Shelley E Kopriva, Valorie L Chiasson, Samantha J Allen, Ajay M Narayanan, Kristina J Young, Kathleen A Jones, Thomas J Kuehl, Brett M Mitchell   +10 more
doaj   +1 more source

Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis [PDF]

, 2010
Background Previously we reported that mice deficient in toll-like receptor 4 (TLR-4) signalling were protected from diet-induced non-alcoholic steatohepatitis (NASH).
Chantal A Rivera, LaTausha Gaskin, Monique Allman, Jia Pang, Kristen Brady, Patrick Adegboyega, Kevin Pruitt, G Tarantino, TM Dall, S Lopez, AH Lichtenstein, F Kim, NA West, G Musso, JY Lee, H Li, JY Lee, AR Weatherill, P Kougias, E Maloney, CA Rivera, O Takeuchi, K Hoebe, RS McCuskey, R Kirsch, A Sahai, CA Rivera, TJ Anderson, JB Keogh, AA Nanji, AA Nanji, AA Nanji, AA Nanji, M You, G Szabo, P Brun, A Abergel, M Allman   +37 more
core   +1 more source

Effects of toll like receptor 4 (TLR4) and toll like receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients

Frontiers in Immunology
IntroductionIn this retrospective study, it was aimed to evaluate effects of Toll Like Receptor 4 (TLR4) and Toll Like Receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients.MethodsA total of 108 acute non ...
Ender Anılır, Filiz Özen, İbrahim Halil Yıldırım   +2 more
doaj   +1 more source

High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer

Tumor Biology, 2017
High mobility group box 1 and toll-like receptor 4/myeloid differentiation factor 88 signaling pathway have been indicated to have oncogenic effects in many cancers.
Yanqiu Yue, Tao Zhou, Yanjing Gao, Zongli Zhang, Li Li, Lin Liu, Wenna Shi, Lihui Su, Baoquan Cheng   +8 more
doaj   +1 more source

Species-Specific Recognition of Aspergillus fumigatus by Toll-like Receptor 1 and Toll-like Receptor 6 [PDF]

, 2017
Background. Aspergillus fumigatus causes invasive aspergillosis, a potentially fatal infection in oncohematological patients. Innate immune detection of A. fumigatus involves Toll-like receptor (TLR) 4 and TLR2, which forms a heterodimer with either TLR1
Bochud, Pierre-Yves, Boeckh, Michael, Calandra, Thierry, Coste, Alix, Jaton, Katia, Latgé, Jean-Paul, Le Roy, Didier, Monod, Michel, Roger, Thierry, Rubino, Ivana   +9 more
core  

Lactobacillus acidophilus induces a slow but more sustained chemokine and cytokine response in naive foetal enterocytes compared to commensal Escherichia coli [PDF]

, 2010
The first exposure to microorganisms at mucosal surfaces is critical for immune maturation and gut health. Facultative anaerobic bacteria are the first to colonise the infant gut, and the impact of these bacteria on intestinal epithelial cells (IEC) may ...
Zeuthen, Louise, Fink, Lisbeth Nielsen, Metzdorff, Stine B, Kristensen, Matilde Bylov, Licht, Tine Rask, Nellemann, Christine Lydia, Frøkiær, Hanne   +6 more
core   +2 more sources

Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. [PDF]

, 2019
We previously reported that the canonical innate immune receptor toll-like receptor 4 (TLR4) is critical in maintaining lung integrity. However, the molecular mechanisms via which TLR4 mediates its effect remained unclear.
Ardito, Taylor, Hwangbo, Cheol, Kim, So-Jin, Lee, Patty J, Li, Alfred, Min, Jin-Na, Peng, Tien, Sauler, Maor, Shan, Peiying, Zhang, Xuchen, Zhang, Yi   +10 more
core   +1 more source