Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer [PDF]
Tumor Biology, 2018 Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...
Mira A Lanki +6 more
doaj +5 more sources
Ulvan Activates Chicken Heterophils and Monocytes Through Toll-Like Receptor 2 and Toll-Like Receptor 4 [PDF]
Frontiers in Immunology, 2018 Responsiveness to invasive pathogens, clearance via the inflammatory response, and activation of appropriate acquired responses are all coordinated by innate host defenses.
Nathalie Guriec +6 more
doaj +3 more sources
EXPRESSION FEATURES OF TOLL-LIKE RECEPTOR 2 AND TOLL-LIKE RECEPTOR 4 IN CHILDREN WITH ASTHMA
Медицинская иммунология, 2017 Currently actively discussed the role of innate immunity receptors, in particular TLRs in the immunopathogenesis of bronchial asthma (BA).The aim of our work was to study the expression of ТLR2 and TLR4 on the nasal mucosal cells and peripheral ...
L. V. Gankovskaya +7 more
doaj +3 more sources
Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice.
PLoS ONE, 2013 Systemic lupus erythematosus is an autoimmune disease with a high morbidity and nephritis is a common manifestation. Previous studies in murine lupus models have suggest a role for Toll-like receptor 2 and 4.
Simon J Freeley +5 more
doaj +4 more sources
Effects of toll like receptor 4 (TLR4) and toll like receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients [PDF]
Frontiers in ImmunologyIntroductionIn this retrospective study, it was aimed to evaluate effects of Toll Like Receptor 4 (TLR4) and Toll Like Receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients.MethodsA total of 108 acute non ...
Ender Anılır +2 more
doaj +2 more sources
Toll-like receptor 2 and Toll-like receptor 4 polymorphisms in invasive pneumococcal disease
Microbes and Infection, 2006 Toll-like receptors (TLRs) recognize distinct pathogen-associated molecular patterns and trigger anti-microbial host defense responses. Several in vitro and in vivo studies in mice indicate that TLR2 and TLR4 are involved in the defense against Streptococcus pneumoniae. Studies have revealed associations between polymorphisms in TLRs and human diseases.
Leen Moens +6 more
openalex +4 more sources
N-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interaction [PDF]
, 2015 FADD (Fas–associated death domain) and TRADD (Tumor Necrosis Factor Receptor 1-associated death domain) proteins are important regulators of cell fate in mammalian cells. They are both involved in death receptors mediated signaling pathways and have been
Balog, Edward M. +7 more
core +27 more sources
How Toll-like receptors influence Parkinson’s disease in the microbiome–gut–brain axis
Frontiers in Immunology, 2023 Recently, a large number of experimenters have found that the pathogenesis of Parkinson’s disease may be related to the gut microbiome and proposed the microbiome–gut–brain axis.
Ziyi Zhang +4 more
doaj +1 more source
Response of Human Toll–Like Receptor 2 During the Infection of Leptospirosis
International Journal of Infectious Diseases, 2022 Purpose: Since Toll-like receptor2 (TLR2) plays a key role in mediating the innate immune responses in mice models against leptospirosis, we aimed to determine the response of human TLR2 during the infection of pathogenic Leptospira spp.
C. Kappagoda +5 more
doaj +1 more source
Medical Journal of Babylon, 2023 Background and Objectives: This study aimed to examine the levels of the toll-like receptors TLR4 and TLR2 in the blood and saliva of patients with coronavirus disease-2019 (COVID-19) receiving orthodontic care in Babylon Province. Materials and Methods:
Basma Abdel Khaleq Eidan +2 more
doaj +1 more source