Results 21 to 30 of about 225,548 (263)

Polymorphisms in vitamin D receptor, toll-like receptor 2 and Toll-Like receptor 4 genes links with Dengue susceptibility [PDF]

Bioinformation, 2021
Host genetic factors are known to determine disease susceptibility in dengue virus infection. Therefore, in this study association of gene polymorphisms of Vitamin D Receptor [rs731236 (Taq) and rs7975232(Apa1)], Toll-like receptor 2 [rs5743708(Arg735Gln) and rs5743704(Pro631His)] and Toll-like receptor 4 [rs4986790A/G(Asp299Gly13843) and rs4986791 C/T(
Singh, Arvind Kumar, Prakash, Shantanu, Garg, RK, Jain, Parul, Kumar, Rashmi, Jain, Amita   +5 more
openaire   +2 more sources

K63-Linked Polyubiquitination on TRAF6 Regulates LPS-Mediated MAPK Activation, Cytokine Production, and Bacterial Clearance in Toll-Like Receptor 7/8 Primed Murine Macrophages

Frontiers in Immunology, 2018
Post viral infection bacterial pneumonia is a major cause of morbidity and mortality associated with both seasonal and pandemic influenza virus illness.
Jaya Talreja, Lobelia Samavati, Lobelia Samavati   +2 more
doaj   +1 more source

Polymorphisms of toll-like receptor 2 and 4 genes in Chagas disease

Memorias do Instituto Oswaldo Cruz, 2008
The aim of this study was to test the possible implication of toll-like receptor 2 (TLR2) and TLR4 gene polymorphisms in determining the susceptibility to Chagas' disease. Genotypes were determined by polymerase chain reaction-restriction fragment length
German Zafra, Oscar Flórez, Carlos A. Morillo, Luis Eduardo Echeverría, Javier Martín, Clara Isabel González   +5 more
doaj   +1 more source

TLR‐2 and TLR‐4 expression in monocytes of newborns with late‐onset sepsis

Jornal de Pediatria (Versão em Português), 2014
Objective: To analyze toll‐like receptor (TLR)‐2 and TLR‐4 expression in monocytes of newborns with late‐onset sepsis. Methods: This prospective study included 27 full‐term newborns aged 8 to 29 days, with clinical and laboratory diagnosis of late‐onset ...
Ana C.C. Redondo, Maria E.J.R. Ceccon, Ana L. Silveira‐Lessa, Camila Quinello, Patrícia Palmeira, Werther B. Carvalho, Magda Carneiro‐Sampaio   +6 more
doaj   +3 more sources

Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis

Journal of Infection in Developing Countries, 2015
Introduction: Clonorchis sinensis is one of the most important foodborne pathogens in humans, and can cause biliary diseases such as gallstones, cholecystitis, cholangitis, and cholangiocarcinoma.
Chao Yan, Xiang-Yang Li, Bo Li, Bei-Bei Zhang, Jiang-Tao Xu, Hui Hua, Qian Yu, Zhuan-Zhuan Liu, Lin-Lin Fu, Ren-Xian Tang, Kui-Yang Zheng   +10 more
doaj   +1 more source

Evaluation of toll-like receptors 2 and 4 polymorphism and intestinal microbiota in children with food allergies

The Turkish Journal of Pediatrics, 2023
Background. Mutual regulation between immune system and gut microbiota is achieved through several mechanisms including the engagement of toll-like receptors (TLRs) which is expressed on numerous cell types.
Mehmet Kılıç, Elif Beyazıt, Ebru Etem Önalan, Tuğçe Kaymaz, Erdal Taşkın   +4 more
doaj   +1 more source

Expression and function of toll-like receptor 2 in vertebrate

Acta Histochemica, 2023
Toll-like receptors (TLRs) are essential for identifying and detecting pathogen-associated molecular patterns (PAMPs) produced by a variety of pathogens, including viruses and bacteria. Since TLR2 is the only TLR capable of creating functional heterodimers with more than two other TLR types, it is very important for vertebrate immunity.
Pergolizzi, Simona, Fumia, Angelo, D'Angelo, Roberta, Mangano, Angelica, Lombardo, Giorgia Pia, Giliberti, Angelo, Messina, Emmanuele, Alesci, Alessio, Lauriano, Eugenia Rita   +8 more
openaire   +2 more sources

The expression of TLR2 and TLR4 in the kidneys and heart of mice infected with Acanthamoeba spp.

Parasites & Vectors, 2020
Background Acanthamoeba spp. are cosmopolitan protozoans that cause infections in the brain, as well as extracerebral infections in the cornea, lungs and skin.
Karolina Kot, Danuta Kosik-Bogacka, Agnieszka Wojtkowiak-Giera, Agnieszka Kolasa-Wołosiuk, Natalia Łanocha-Arendarczyk   +4 more
doaj   +1 more source

Toll-like receptor 2 and type 2 diabetes

Cellular & Molecular Biology Letters, 2016
Innate immunity plays a crucial role in the pathogenesis of type 2 diabetes and related complications. Since the toll-like receptors (TLRs) are central to innate immunity, it appears that they are important participants in the development and pathogenesis of the disease.
Sepehri, Zahra, Kiani, Zohre, Nasiri, Ali Akbar, Kohan, Farhad   +3 more
openaire   +2 more sources

Modulation of atherosclerosis in mice by Toll-like receptor 2 [PDF]

Journal of Clinical Investigation, 2005
Epidemiologic evidence has established a relationship between microbial infection and atherosclerosis. Mammalian TLRs provide clues on the mechanism of this inflammatory cascade. TLR2 has a large ligand repertoire that includes bacterial-derived exogenous and possibly host-derived endogenous ligands.
Adam E, Mullick, Peter S, Tobias, Linda K, Curtiss   +2 more
openaire   +2 more sources